caa a22 4500 445376651 CHVBK 20180317143004.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00702-010-0511-7 doi (NATIONALLICENCE)springer-10.1007/s00702-010-0511-7 What can Drosophila teach us about iron-accumulation neurodegenerative disorders? [Elektronische Daten] [Uriya Bekenstein, Sebastian Kadener] The present review focuses on the development and use of Drosophila for modeling neurodegenerative disorders that involve iron accumulation, in particular Friedrich's Ataxia (FRDA) and Neurodegeneration with Iron accumulation (NBIA). Several Drosophila models of such disorders have been introduced successfully in the last few years. Here we review these models and note on the feasibility and advantages of using fly models for understanding the molecular and cellular bases of these devastating diseases. Springer-Verlag, 2010 Neurodegeneration nationallicence FRDA nationallicence NBIA nationallicence Drosophila nationallicence Iron accumulation nationallicence Bekenstein Uriya Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat-Ram, 91904, Jerusalem, Israel aut Kadener Sebastian Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat-Ram, 91904, Jerusalem, Israel aut Journal of Neural Transmission Springer Vienna 118/3(2011-03-01), 389-396 0300-9564 118:3<389 2011 118 702 https://doi.org/10.1007/s00702-010-0511-7 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0511-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bekenstein Uriya Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat-Ram, 91904, Jerusalem, Israel aut NATIONALLICENCE 700 1- Kadener Sebastian Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat-Ram, 91904, Jerusalem, Israel aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/3(2011-03-01), 389-396 0300-9564 118:3<389 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer