caa a22 4500 445376872 CHVBK 20180317143005.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00702-010-0547-8 doi (NATIONALLICENCE)springer-10.1007/s00702-010-0547-8 The pedunculopontine nucleus as a target for deep brain stimulation [Elektronische Daten] [Clement Hamani, Elena Moro, Andres Lozano] The pedunculopontine nucleus (PPN) is a brain stem locomotive center that is also involved in the processing of sensory and behavioral information. The PPN has been recently proposed as a potential target for the treatment of axial symptoms in Parkinson's disease (PD). To date, results of the first series of PD patients treated with PPN deep brain stimulation (DBS) have shown promising results. In this article, we review some of the basic aspects of the PPN as a target and the outcome of the recently published clinical trials. Springer-Verlag, 2010 Pedunculopontine nucleus nationallicence Parkinson's disease nationallicence Surgery nationallicence Deep brain stimulation nationallicence Gait nationallicence Falls nationallicence Sleep nationallicence Hamani Clement Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street WW 4-447, M5T2S8, Toronto, ON, Canada aut Moro Elena Division of Neurology, Department of Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada aut Lozano Andres Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street WW 4-447, M5T2S8, Toronto, ON, Canada aut Journal of Neural Transmission Springer Vienna 118/10(2011-10-01), 1461-1468 0300-9564 118:10<1461 2011 118 702 https://doi.org/10.1007/s00702-010-0547-8 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0547-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hamani Clement Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street WW 4-447, M5T2S8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Moro Elena Division of Neurology, Department of Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Lozano Andres Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street WW 4-447, M5T2S8, Toronto, ON, Canada aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/10(2011-10-01), 1461-1468 0300-9564 118:10<1461 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer