caa a22 4500 445376937 CHVBK 20180317143005.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00702-011-0631-8 doi (NATIONALLICENCE)springer-10.1007/s00702-011-0631-8 Pedunculopontine stimulation from primate to patient [Elektronische Daten] [Erlick Pereira, Dipankar Nandi, Ned Jenkinson, John Stein, Alexander Green, Tipu Aziz] Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson's disease and related disorders. Here we summarise our non-human primate investigations of relevance to our surgical targeting of the PPN and relate the primate research to initial clinical experience of PPN DBS. Springer-Verlag, 2011 Deep brain stimulation nationallicence Parkinson's disease nationallicence Pedunculopontine nucleus nationallicence Primate research nationallicence Diffusion tensor imaging nationallicence Pereira Erlick Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut Nandi Dipankar Imperial College Neuromodulation Group, Charing Cross Hospital and Division of Neuroscience and Mental Health, Imperial College London, London, UK aut Jenkinson Ned Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut Stein John Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut Green Alexander Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut Aziz Tipu Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut Journal of Neural Transmission Springer Vienna 118/10(2011-10-01), 1453-1460 0300-9564 118:10<1453 2011 118 702 https://doi.org/10.1007/s00702-011-0631-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-011-0631-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pereira Erlick Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut NATIONALLICENCE 700 1- Nandi Dipankar Imperial College Neuromodulation Group, Charing Cross Hospital and Division of Neuroscience and Mental Health, Imperial College London, London, UK aut NATIONALLICENCE 700 1- Jenkinson Ned Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut NATIONALLICENCE 700 1- Stein John Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut NATIONALLICENCE 700 1- Green Alexander Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut NATIONALLICENCE 700 1- Aziz Tipu Oxford Functional Neurosurgery, Department of Neurological Surgery, The West Wing, The John Radcliffe Hospital, OX3 9DU, Oxford, UK aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/10(2011-10-01), 1453-1460 0300-9564 118:10<1453 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer