caa a22 4500 445376988 CHVBK 20180317143005.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00702-010-0544-y doi (NATIONALLICENCE)springer-10.1007/s00702-010-0544-y Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia? [Elektronische Daten] [Christian Blahak, Hans-Holger Capelle, Hansjoerg Baezner, Thomas Kinfe, Michael Hennerici, Joachim Krauss] Recently parkinsonism has been reported as a rare side effect of globus pallidus internus (GPi) deep brain stimulation (DBS) for dystonia. In the present systematic prospective study in 11 patients with segmental dystonia not affecting distal arm function, we could demonstrate significant changes in handwriting characterized by mild micrographia following GPi-DBS. We propose that this finding reflects GPi-DBS-induced disturbances of basal ganglia function in terms of a mild hypokinetic syndrome, as a result of outflow alterations in pallido-thalamo-cortical pathways. Springer-Verlag, 2011 Dystonia nationallicence Deep brain stimulation nationallicence Globus pallidus internus nationallicence Micrographia nationallicence Hypokinesia nationallicence Blahak Christian Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut Capelle Hans-Holger Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut Baezner Hansjoerg Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut Kinfe Thomas Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut Hennerici Michael Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut Krauss Joachim Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 549-553 0300-9564 118:4<549 2011 118 702 https://doi.org/10.1007/s00702-010-0544-y text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0544-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blahak Christian Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut NATIONALLICENCE 700 1- Capelle Hans-Holger Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut NATIONALLICENCE 700 1- Baezner Hansjoerg Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut NATIONALLICENCE 700 1- Kinfe Thomas Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut NATIONALLICENCE 700 1- Hennerici Michael Department of Neurology, Universitaetsmedizin Mannheim, UMM, University of Heidelberg, Theodor-Kutzer Ufer 1-3, 68167, Mannheim, Germany aut NATIONALLICENCE 700 1- Krauss Joachim Department of Neurosurgery, Medical School Hannover, MHH, Hannover, Germany aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 549-553 0300-9564 118:4<549 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer