caa a22 4500 445377011 CHVBK 20180317143005.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00702-010-0566-5 doi (NATIONALLICENCE)springer-10.1007/s00702-010-0566-5 Epilepsy and other central nervous system diseases in atypical autism: a case control study [Elektronische Daten] [Svend Mouridsen, Bente Rich, Torben Isager] There is an increased but variable risk of epilepsy in autism spectrum disorders. The objective of this study is to compare the prevalence and types of epilepsy and other central nervous system (CNS) diseases in a clinical sample of 89 individuals diagnosed as children with atypical autism (AA) with 258 matched controls from the general population. Diagnoses were based on data from the nationwide Danish National Hospital Register. The average observation time was 32.9years, and mean age at follow-up was 48.5years. Of the 89 individuals with AA, 20 (22.5%) were registered with at least one epilepsy diagnosis against 11 (4.3%) in the comparison group (P<0.0001; OR 6.5; 95% CI 3.0-14.2). Other CNS diseases occurred with low frequency in both groups, and no single CNS disease (except epilepsy) was significantly more frequent among patients with AA. Low intelligence was a risk factor for epilepsy in AA. Springer-Verlag, 2010 Atypical autism nationallicence Epilepsy nationallicence Longitudinal study nationallicence Mouridsen Svend Department of Child and Adolescent Psychiatry, Bispebjerg University Hospital, 2400, Copenhagen, Denmark aut Rich Bente International Rehabilitation Council for Torture Victims, Copenhagen, Denmark aut Isager Torben Centre for Child and Adolescent Psychiatry, Glostrup University Hospital, Glostrup, Denmark aut Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 621-627 0300-9564 118:4<621 2011 118 702 https://doi.org/10.1007/s00702-010-0566-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0566-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mouridsen Svend Department of Child and Adolescent Psychiatry, Bispebjerg University Hospital, 2400, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Rich Bente International Rehabilitation Council for Torture Victims, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Isager Torben Centre for Child and Adolescent Psychiatry, Glostrup University Hospital, Glostrup, Denmark aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 621-627 0300-9564 118:4<621 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer