caa a22 4500 445377097 CHVBK 20180317143006.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00702-011-0589-6 doi (NATIONALLICENCE)springer-10.1007/s00702-011-0589-6 Controversies in neurology: asymptomatic carotid stenosis—intervention or just stick to medical therapy. The argument for carotid endarterectomy [Elektronische Daten] [Liam Hirt, Alison Halliday] Patients with a significant carotid stenosis are at an increased risk of suffering from a potentially fatal or disabling stroke. The current management strategies available to a patient with an asymptomatic carotid stenosis are either medical therapy alone, or in combination with either carotid endarterectomy, or carotid angioplasty and stenting. Medical therapy alone can reduce the incidence of stroke in general, but whether there is any reduction in stroke attributable to a significant carotid stenosis is less clear. Carotid endarterectomy, on the other hand, has been shown to reduce the incidence of ipsilateral ischaemic stroke in both symptomatic and asymptomatic patients, with the benefits extending into the long-term. Carotid angioplasty and stenting is a newer technique with the benefit of being minimally invasive. The results of trials comparing the technique to endarterectomy have had conflicting results, and the results of large multi-centre trials are awaited. Currently the safest strategy for a patient with a significant asymptomatic carotid stenosis consists of optimal medical therapy with carotid endarterectomy for those less than 75years of age, who are suitable for surgery. Springer-Verlag, 2011 Angioplasty nationallicence Asymptomatic nationallicence Carotid nationallicence Endarterectomy nationallicence Stenosis nationallicence Stenting nationallicence Stroke nationallicence Hirt Liam CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, OX3 7LF, Oxford, UK aut Halliday Alison St George's Hospital, Tooting, SW17 0QT, London, UK aut Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 631-636 0300-9564 118:4<631 2011 118 702 https://doi.org/10.1007/s00702-011-0589-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-011-0589-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hirt Liam CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, OX3 7LF, Oxford, UK aut NATIONALLICENCE 700 1- Halliday Alison St George's Hospital, Tooting, SW17 0QT, London, UK aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/4(2011-04-01), 631-636 0300-9564 118:4<631 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer