caa a22 4500 445377194 CHVBK 20180317143006.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00702-011-0584-y doi (NATIONALLICENCE)springer-10.1007/s00702-011-0584-y Extranigral extension of structural midbrain lesions overshadows parkinsonism [Elektronische Daten] [Hee Kim, Ji Yun, Jong-Min Kim, Yu Kim, Gwanhee Erm, Sang Kim, Beom Jeon] We report on a clinicoanatomical analysis of five patients with structural midbrain lesions who shared severe nigrostriatal dopaminergic denervation but presented different involuntary movements. The main clinical phenotype was parkinsonism in only one case; it was choreoballism in three cases and tremor and dystonia in one case. Structural midbrain lesions are likely to involve structures additional to nigral dopaminergic neurons. The extent of extranigral involvement may determine the diverse clinical manifestations associated with the structural midbrain lesions. Springer-Verlag, 2011 Midbrain nationallicence Parkinsonism nationallicence Dystonia nationallicence Chorea nationallicence Dopamine transporter imaging nationallicence Kim Hee Department of Neurology, Konkuk University Hospital, Seoul, Korea aut Yun Ji Department of Neurology, Seoul National University Bundang Hospital, Seoul, Korea aut Kim Jong-Min Department of Neurology, Seoul National University Bundang Hospital, Seoul, Korea aut Kim Yu Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, Korea aut Erm Gwanhee Parkinson Study Group, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea aut Kim Sang Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, Korea aut Jeon Beom Parkinson Study Group, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea aut Journal of Neural Transmission Springer Vienna 118/8(2011-08-01), 1209-1213 0300-9564 118:8<1209 2011 118 702 https://doi.org/10.1007/s00702-011-0584-y text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-011-0584-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Hee Department of Neurology, Konkuk University Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Yun Ji Department of Neurology, Seoul National University Bundang Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Jong-Min Department of Neurology, Seoul National University Bundang Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Yu Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Erm Gwanhee Parkinson Study Group, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Sang Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Jeon Beom Parkinson Study Group, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/8(2011-08-01), 1209-1213 0300-9564 118:8<1209 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer