caa a22 4500 445377224 CHVBK 20180317143006.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00702-011-0606-9 doi (NATIONALLICENCE)springer-10.1007/s00702-011-0606-9 Brain activity associated with pain, hyperalgesia and allodynia: an ALE meta-analysis [Elektronische Daten] [Stefan Lanz, Frank Seifert, Christian Maihöfner] The use of functional brain imaging techniques offers the possibility of uncovering the cerebral processing of the human pain experience. In recent years, many imaging studies have focused on defining a network of brain structures involved in the processing of normal pain. Additionally, it has been shown that stimulus-evoked pain, which is a frequent symptom of neuropathic pain, causes distinct patterns of brain activation. In the present study, we quantitatively analyzed the data of previous functional imaging studies. Studies were thus collected by means of a MEDLINE query. A meta-analysis using the activation-likelihood estimation method was conducted to quantify the acquired results. We then used this data to summarize and compare the cerebral activations of (i) normal and stimulus-evoked pain, (ii) thermal and mechanical pain, (iii) different types of stimulus-evoked pain (hyperalgesia, allodynia), and (iv) clinical neuropathic and experimental pain. The results suggest the existence of distinct, although overlapping, neuronal networks related to these different types of pain. Springer-Verlag, 2011 Allodynia nationallicence Cerebral activation nationallicence Functional imaging nationallicence Hyperalgesia nationallicence Neuropathic nationallicence Experimental nationallicence Nociception nationallicence Lanz Stefan Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut Seifert Frank Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut Maihöfner Christian Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut Journal of Neural Transmission Springer Vienna 118/8(2011-08-01), 1139-1154 0300-9564 118:8<1139 2011 118 702 https://doi.org/10.1007/s00702-011-0606-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-011-0606-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lanz Stefan Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut NATIONALLICENCE 700 1- Seifert Frank Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut NATIONALLICENCE 700 1- Maihöfner Christian Department of Neurology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/8(2011-08-01), 1139-1154 0300-9564 118:8<1139 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer