caa a22 4500 445377720 CHVBK 20180317143008.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00702-010-0540-2 doi (NATIONALLICENCE)springer-10.1007/s00702-010-0540-2 Neural correlates of spontaneous panic attacks [Elektronische Daten] [Thomas Dresler, Tim Hahn, Michael Plichta, Lena Ernst, Sara Tupak, Ann-Christine Ehlis, Bodo Warrings, Jürgen Deckert, Andreas Fallgatter] In this report, we present two anxiety disorder patients who spontaneously experienced a panic attack during an fMRI examination and subsequently aborted the measurement. We analyzed the functional data gathered up to that point in relation to the patients' subsequent verbal reports of the course of the panic attacks. Within prominent structures of the fear network (amygdala, insula, prefrontal cortex) neural dynamics mirrored the description of the attack very well for one of the patients. For the other patient who experienced a less intense attack and who was treated pharmacologically at the time of measurement, the relation was limited to the prefrontal cortex. Investigating the temporal dynamics of neural activation in an ecologically valid situation may point to the potentially different roles of the amygdala and the insula as well as the prefrontal cortex prior to and during a panic attack. Springer-Verlag, 2010 Panic attack nationallicence fMRI nationallicence Insula nationallicence Amygdala nationallicence Prefrontal cortex nationallicence Dresler Thomas Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Hahn Tim Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Plichta Michael Department of Psychiatry, Division for Imaging in Psychiatry, Central Institute of Mental Health, Mannheim, Germany aut Ernst Lena Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Tupak Sara Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Ehlis Ann-Christine Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Warrings Bodo Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Wuerzburg, Germany aut Deckert Jürgen Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Wuerzburg, Germany aut Fallgatter Andreas Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut Journal of Neural Transmission Springer Vienna 118/2(2011-02-01), 263-269 0300-9564 118:2<263 2011 118 702 https://doi.org/10.1007/s00702-010-0540-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00702-010-0540-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dresler Thomas Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Hahn Tim Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Plichta Michael Department of Psychiatry, Division for Imaging in Psychiatry, Central Institute of Mental Health, Mannheim, Germany aut NATIONALLICENCE 700 1- Ernst Lena Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Tupak Sara Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Ehlis Ann-Christine Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Warrings Bodo Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Deckert Jürgen Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Wuerzburg, Germany aut NATIONALLICENCE 700 1- Fallgatter Andreas Psychophysiology and Functional Imaging, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, Fuechsleinstr 15, 97080, Wuerzburg, Germany aut NATIONALLICENCE 773 0- Journal of Neural Transmission Springer Vienna 118/2(2011-02-01), 263-269 0300-9564 118:2<263 2011 118 702 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer