caa a22 4500 445377917 CHVBK 20180317143008.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10393-010-0355-5 doi (NATIONALLICENCE)springer-10.1007/s10393-010-0355-5 Using Remote Sensing to Map the Risk of Human Monkeypox Virus in the Congo Basin [Elektronische Daten] [Trevon Fuller, Henri Thomassen, Prime Mulembakani, Sara Johnston, James Lloyd-Smith, Neville Kisalu, Timothee Lutete, Seth Blumberg, Joseph Fair, Nathan Wolfe, Robert Shongo, Pierre Formenty, Hermann Meyer, Linda Wright, Jean-Jacques Muyembe, Wolfgang Buermann, Sassan Saatchi, Emile Okitolonda, Lisa Hensley, Thomas Smith, Anne Rimoin] Although the incidence of human monkeypox has greatly increased in Central Africa over the last decade, resources for surveillance remain extremely limited. We conducted a geospatial analysis using existing data to better inform future surveillance efforts. Using active surveillance data collected between 2005 and 2007, we identified locations in Sankuru district, Democratic Republic of Congo (DRC) where there have been one or more cases of human monkeypox. To assess what taxa constitute the main reservoirs of monkeypox, we tested whether human cases were associated with (i) rope squirrels (Funisciurus sp.), which were implicated in monkeypox outbreaks elsewhere in the DRC in the 1980s, or (ii) terrestrial rodents in the genera Cricetomys and Graphiurus, which are believed to be monkeypox reservoirs in West Africa. Results suggest that the best predictors of human monkeypox cases are proximity to dense forests and associated habitat preferred by rope squirrels. The risk of contracting monkeypox is significantly greater near sites predicted to be habitable for squirrels (OR=1.32; 95% CI 1.08-1.63). We recommend that semi-deciduous rainforests with oil-palm, the rope squirrel's main food source, be prioritized for monitoring. The Author(s), 2010 monkeypox nationallicence orthopoxvirus nationallicence smallpox vaccination nationallicence epidemiology nationallicence active surveillance nationallicence human transmission nationallicence Fuller Trevon Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut Thomassen Henri Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut Mulembakani Prime Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut Johnston Sara United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA aut Lloyd-Smith James Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut Kisalu Neville Department of Microbiology, University of California, Los Angeles, CA, USA aut Lutete Timothee Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut Blumberg Seth Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut Fair Joseph Global Viral Forecasting Initiative, San Francisco, CA, USA aut Wolfe Nathan Global Viral Forecasting Initiative, San Francisco, CA, USA aut Shongo Robert Ministry of Health, Kinshasa, Democratic Republic of Congo aut Formenty Pierre Department of Global Alert and Response, World Health Organization, Geneva, Switzerland aut Meyer Hermann Bundeswehr Institute of Microbiology, Munich, Germany aut Wright Linda The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA aut Muyembe Jean-Jacques National Institute of Biomedical Research, Kinshasa, Democratic Republic of Congo aut Buermann Wolfgang Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut Saatchi Sassan Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut Okitolonda Emile Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut Hensley Lisa United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA aut Smith Thomas Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut Rimoin Anne Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut EcoHealth Springer-Verlag 8/1(2011-03-01), 14-25 1612-9202 8:1<14 2011 8 10393 https://doi.org/10.1007/s10393-010-0355-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10393-010-0355-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fuller Trevon Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Thomassen Henri Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Mulembakani Prime Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut NATIONALLICENCE 700 1- Johnston Sara United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA aut NATIONALLICENCE 700 1- Lloyd-Smith James Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Kisalu Neville Department of Microbiology, University of California, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Lutete Timothee Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut NATIONALLICENCE 700 1- Blumberg Seth Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Fair Joseph Global Viral Forecasting Initiative, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Wolfe Nathan Global Viral Forecasting Initiative, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Shongo Robert Ministry of Health, Kinshasa, Democratic Republic of Congo aut NATIONALLICENCE 700 1- Formenty Pierre Department of Global Alert and Response, World Health Organization, Geneva, Switzerland aut NATIONALLICENCE 700 1- Meyer Hermann Bundeswehr Institute of Microbiology, Munich, Germany aut NATIONALLICENCE 700 1- Wright Linda The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Muyembe Jean-Jacques National Institute of Biomedical Research, Kinshasa, Democratic Republic of Congo aut NATIONALLICENCE 700 1- Buermann Wolfgang Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Saatchi Sassan Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Okitolonda Emile Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo aut NATIONALLICENCE 700 1- Hensley Lisa United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA aut NATIONALLICENCE 700 1- Smith Thomas Center for Tropical Research, Institute of the Environment, University of California, Los Angeles, 619 Charles E. Young Dr. East, 90095-1496, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Rimoin Anne Fogarty International Center, National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 773 0- EcoHealth Springer-Verlag 8/1(2011-03-01), 14-25 1612-9202 8:1<14 2011 8 10393 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer