caa a22 4500 445378301 CHVBK 20180317143010.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10393-011-0725-7 doi (NATIONALLICENCE)springer-10.1007/s10393-011-0725-7 Rodent-Borne Hantaviruses in Cambodia, Lao PDR, and Thailand [Elektronische Daten] [Kim Blasdell, Jean Cosson, Yannick Chaval, Vincent Herbreteau, Bounneuang Douangboupha, Sathaporn Jittapalapong, Ake Lundqvist, Jean-Pierre Hugot, Serge Morand, Philippe Buchy] In order to evaluate the circulation of hantaviruses present in southeast Asia, a large scale survey of small mammal species was carried out at seven main sites in the region (Cambodia, Lao People's Democratic Republic, and Thailand). Small scale opportunistic trapping was also performed at an eighth site (Cambodia). Using a standard IFA test, IgG antibodies reacting to Hantaan virus antigens were detected at six sites. Antibody prevalence at each site varied from 0 to 5.6% with antibodies detected in several rodent species (Bandicota indica, B. savilei, Maxomys surifer, Mus caroli, M. cookii, Rattus exulans, R. nitidius, R. norvegicus, and R. tanezumi). When site seroprevalence was compared with site species richness, seropositive animals were found more frequently at sites with lower species richness. In order to confirm which hantavirus species were present, a subset of samples was also subjected to RT-PCR. Hantaviral RNA was detected at a single site from each country. Sequencing confirmed the presence of two hantavirus species, Thailand and Seoul viruses, including one sample (from Lao PDR) representing a highly divergent strain of Seoul virus. This is the first molecular evidence of hantavirus in Lao PDR and the first reported L segment sequence data for Thailand virus. International Association for Ecology and Health, 2011 hantavirus nationallicence southeast Asia nationallicence rodents nationallicence serology nationallicence phylogeny nationallicence seoul virus variant nationallicence Blasdell Kim Virology Unit, Institut Pasteur du Cambodge, 5 Monivong Boulevard, BP 983, Phnom Penh, Cambodia aut Cosson Jean INRA, UMR CBGP (INRA/IRD/Cirad/Montpellier SupAgro), Campus International de Baillarguet, CS 30016, 34988, Montferrier sur Lez, France aut Chaval Yannick Centre de Biologie et de Gestion et des Populations (CBGP), International de Baillarguet, CS 30016, 34988, Montferrier sur lez, France aut Herbreteau Vincent CIRAD, UR AGIRs (Animal et Gestion Intégrée des Risques), Campus International de Baillarguet, Montpellier, France aut Douangboupha Bounneuang National Agricultural Research Centre, National Agricultural and Forestry Research Institute, Vientiane, Lao PDR aut Jittapalapong Sathaporn Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, 10900, Bangkok, Thailand aut Lundqvist Ake Swedish Institute for Infectious Disease Control, Stockholm, Sweden aut Hugot Jean-Pierre Origine, Structure et Evolution de la Biodiversite, Museum National d'Histoire Naturelle, Paris, France aut Morand Serge Institut des Sciences de l'Evolution, CNRS, IRD, Université Montpellier 2, CC065, 34095, Montpellier Cedex 05, France aut Buchy Philippe Virology Unit, Institut Pasteur du Cambodge, 5 Monivong Boulevard, BP 983, Phnom Penh, Cambodia aut EcoHealth Springer-Verlag 8/4(2011-12-01), 432-443 1612-9202 8:4<432 2011 8 10393 https://doi.org/10.1007/s10393-011-0725-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10393-011-0725-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blasdell Kim Virology Unit, Institut Pasteur du Cambodge, 5 Monivong Boulevard, BP 983, Phnom Penh, Cambodia aut NATIONALLICENCE 700 1- Cosson Jean INRA, UMR CBGP (INRA/IRD/Cirad/Montpellier SupAgro), Campus International de Baillarguet, CS 30016, 34988, Montferrier sur Lez, France aut NATIONALLICENCE 700 1- Chaval Yannick Centre de Biologie et de Gestion et des Populations (CBGP), International de Baillarguet, CS 30016, 34988, Montferrier sur lez, France aut NATIONALLICENCE 700 1- Herbreteau Vincent CIRAD, UR AGIRs (Animal et Gestion Intégrée des Risques), Campus International de Baillarguet, Montpellier, France aut NATIONALLICENCE 700 1- Douangboupha Bounneuang National Agricultural Research Centre, National Agricultural and Forestry Research Institute, Vientiane, Lao PDR aut NATIONALLICENCE 700 1- Jittapalapong Sathaporn Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, 10900, Bangkok, Thailand aut NATIONALLICENCE 700 1- Lundqvist Ake Swedish Institute for Infectious Disease Control, Stockholm, Sweden aut NATIONALLICENCE 700 1- Hugot Jean-Pierre Origine, Structure et Evolution de la Biodiversite, Museum National d'Histoire Naturelle, Paris, France aut NATIONALLICENCE 700 1- Morand Serge Institut des Sciences de l'Evolution, CNRS, IRD, Université Montpellier 2, CC065, 34095, Montpellier Cedex 05, France aut NATIONALLICENCE 700 1- Buchy Philippe Virology Unit, Institut Pasteur du Cambodge, 5 Monivong Boulevard, BP 983, Phnom Penh, Cambodia aut NATIONALLICENCE 773 0- EcoHealth Springer-Verlag 8/4(2011-12-01), 432-443 1612-9202 8:4<432 2011 8 10393 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer