caa a22 4500 445378476 CHVBK 20180317143010.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10393-011-0710-1 doi (NATIONALLICENCE)springer-10.1007/s10393-011-0710-1 Neurotoxic Sequelae of Mercury Exposure: An Intervention and Follow-up Study in the Brazilian Amazon [Elektronische Daten] [Myriam Fillion, Aline Philibert, Frédéric Mertens, Mélanie Lemire, Carlos Passos, Benoit Frenette, Jean Guimarães, Donna Mergler] Since 1995, the Caruso Project used an Ecosystem Approach to Human Health to examine mercury (Hg) exposure in fish-eating communities in the Brazilian Amazon and develop interventions to maximise nutrition from traditional diet and minimise toxic risk. In 1995, 2000 and 2006, this study followed fish consumption, Hg levels, and visual and motor functions in 31 villagers. Questionnaires gathered information on socio-demographics and diet. Hair Hg (H-Hg) levels were measured. Visual acuity, colour vision, manual dexterity and grip strength were assessed. Data was analysed using general linear models of repeated measures. Total fish consumption, similar in 1995 and 2000, decreased in 2006. Carnivorous fish consumption initially decreased and then remained stable, whereas non-carnivorous fish consumption first increased and then decreased. H-Hg declined from 17.6 to 7.8μg/g. Visual functions showed a significant decrease over time, with those with H-Hg≥20μg/g in 1995 showing greater loss. Motor functions showed initial improvement and then returned to the 1995 performance level. Decrease in Hg exposure is attributed to the intervention and socio-economic changes in the village. While there may be a certain reversibility of motor deficits, visual capacities may decrease progressively with respect to exposure prior to the intervention. International Association for Ecology and Health, 2011 mercury nationallicence fish consumption nationallicence health nationallicence Amazon nationallicence intervention nationallicence ecosystem approach nationallicence Fillion Myriam Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut Philibert Aline Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut Mertens Frédéric Centro de Desenvolvimento Sustentável (CDS), Universidade de Brasília, Brasília, DF, Brazil aut Lemire Mélanie Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut Passos Carlos Faculdade UnB Planaltina, Universidade de Brasília, Planaltina, DF, Brazil aut Frenette Benoit École d'optométrie, Université de Montréal, Montreal, QC, Canada aut Guimarães Jean Laboratório de Traçadores, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil aut Mergler Donna Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut EcoHealth Springer-Verlag 8/2(2011-06-01), 210-222 1612-9202 8:2<210 2011 8 10393 https://doi.org/10.1007/s10393-011-0710-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10393-011-0710-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fillion Myriam Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Philibert Aline Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Mertens Frédéric Centro de Desenvolvimento Sustentável (CDS), Universidade de Brasília, Brasília, DF, Brazil aut NATIONALLICENCE 700 1- Lemire Mélanie Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Passos Carlos Faculdade UnB Planaltina, Universidade de Brasília, Planaltina, DF, Brazil aut NATIONALLICENCE 700 1- Frenette Benoit École d'optométrie, Université de Montréal, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Guimarães Jean Laboratório de Traçadores, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil aut NATIONALLICENCE 700 1- Mergler Donna Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l'environnement (CINBIOSE), Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, H3C 3P8, Montreal, QC, Canada aut NATIONALLICENCE 773 0- EcoHealth Springer-Verlag 8/2(2011-06-01), 210-222 1612-9202 8:2<210 2011 8 10393 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer