caa a22 4500 445388358 CHVBK 20180317143038.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s11144-011-0325-0 doi (NATIONALLICENCE)springer-10.1007/s11144-011-0325-0 Research on the N -alkylation of morpholine with alcohols catalyzed by CuO-NiO/γ-Al2O3 [Elektronische Daten] [Xinzhi Chen, Hu Luo, Chao Qian, Chaohong He] The N-alkylation of morpholine with alcohols in gas-solid phase was investigated in a fixed-bed reactor over CuO-NiO/γ-Al2O3 catalyst prepared by the impregnation method. The N-methylation of morpholine with methanol gave a 95.3% conversion with a 93.8% selectivity of N-methylmorpholine under the optimum reaction condition, and the corresponding apparent activation energy is 46.20kJmol−1. The present catalytic system is also applicable to other low-carbon primary alcohols. However, secondary alcohols enjoy relatively low product selectivity for the resulting ketone is a poorer electrophile than an aldehyde. For cyclohexanol, the low conversion and selectivity are mainly due to steric effects. The catalyst shows a high catalytic activity without obvious fluctuation during a long period of 120h. Akadémiai Kiadó, Budapest, Hungary, 2011 Fixed-bed reactor nationallicence Morpholine nationallicence N -alkylation nationallicence Alcohols nationallicence Catalyst nationallicence Chen Xinzhi State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut Luo Hu State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut Qian Chao State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut He Chaohong State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut Reaction Kinetics, Mechanisms and Catalysis Springer Netherlands 104/1(2011-10-01), 163-171 1878-5190 104:1<163 2011 104 11144 https://doi.org/10.1007/s11144-011-0325-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11144-011-0325-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Xinzhi State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Luo Hu State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Qian Chao State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- He Chaohong State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, 310027, Hangzhou, People's Republic of China aut NATIONALLICENCE 773 0- Reaction Kinetics, Mechanisms and Catalysis Springer Netherlands 104/1(2011-10-01), 163-171 1878-5190 104:1<163 2011 104 11144 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer