caa a22 4500 44539143X CHVBK 20180317143047.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s10955-011-0183-1 doi (NATIONALLICENCE)springer-10.1007/s10955-011-0183-1 Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments [Elektronische Daten] [R. Zia, J. Dong, B. Schmittmann] The phenomenon of protein synthesis has been modeled in terms of totally asymmetric simple exclusion processes (TASEP) since 1968. In this article, we provide a tutorial of the biological and mathematical aspects of this approach. We also summarize several new results, concerned with limited resources in the cell and simple estimates for the current (protein production rate) of a TASEP with inhomogeneous hopping rates, reflecting the characteristics of real genes. Springer Science+Business Media, LLC, 2011 Protein synthesis nationallicence TASEP nationallicence Nonequilibrium statistical physics nationallicence Zia R. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut Dong J. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut Schmittmann B. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut Journal of Statistical Physics Springer US; http://www.springer-ny.com 144/2(2011-07-01), 405-428 0022-4715 144:2<405 2011 144 10955 https://doi.org/10.1007/s10955-011-0183-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10955-011-0183-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zia R. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut NATIONALLICENCE 700 1- Dong J. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut NATIONALLICENCE 700 1- Schmittmann B. Physics Department, Virginia Tech, 24061, Blacksburg, VA, USA aut NATIONALLICENCE 773 0- Journal of Statistical Physics Springer US; http://www.springer-ny.com 144/2(2011-07-01), 405-428 0022-4715 144:2<405 2011 144 10955 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer