caa a22 4500 445794526 CHVBK 20180317145120.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10620-011-1766-z doi (NATIONALLICENCE)springer-10.1007/s10620-011-1766-z The Impact of Post-Infectious Functional Gastrointestinal Disorders and Symptoms on the Health-Related Quality of Life of US Military Personnel Returning from Deployment to the Middle East [Elektronische Daten] [Kashyap Trivedi, Carey Schlett, David Tribble, Marshall Monteville, John Sanders, Mark Riddle] Background and Aim: Mental and physical health-related quality of life (HRQOL) are important health impact measures following military deployment. While conditions such as post-traumatic stress disorder (PTSD) are known to adversely affect QOL, little is known about the effect of post-infectious functional gastrointestinal disorders (PI-FGID). Our aim was to evaluate the risk of PI-FGID and its impact on HRQOL among military personnel returning from deployment. Methods: A cross-sectional cohort of active-duty military deployed to Egypt or Turkey between 2004 and 2005 was asked to complete a questionnaire (Rome II and SF-36 instruments) on travelers' diarrhea (TD) during deployment and FGID symptoms and HRQOL 6months after returning from deployment. Results: A total of 121 military personnel returning from Egypt (n=33) and Turkey (n=88) completed the post-deployment questionnaire. Nearly half (48.3%) met the definition for an FGID at the time of the survey, and 53% of individuals reporting one or more episodes of TD during deployment developed an FGID, compared to 33% of those not reporting TD (odds ratio [OR] 2.2, P=0.08). Compared to those not meeting the FGID criteria, those with post-deployment FGID had lower mean mental HRQOL scores (−13.4%, P<0.0001) and lower physical HRQOL scores (−7.2%, P=0.004). Conclusions: There was a high prevalence of FGID symptoms in military personnel returning from deployment, and TD was a noted risk factor. FGID and symptoms decreased QOL, with mental HRQOL being affected more than physical HRQOL. These findings require further research in order to assess the long-term impact of these and other post-infectious sequela related to TD during deployments among returning veterans. Springer Science+Business Media, LLC (Outside the USA), 2011 Military personnel nationallicence Quality of life nationallicence Functional gastrointestinal disorders nationallicence Travelers' diarrhea nationallicence Epidemiology nationallicence Trivedi Kashyap Division of Gastroenterology, University of California, Irvine, Orange, CA, USA aut Schlett Carey Uniformed Services University of the Health Sciences, Bethesda, MD, USA aut Tribble David Uniformed Services University of the Health Sciences, Bethesda, MD, USA aut Monteville Marshall Navy and Marine Corps Public Health Center, Norfolk, VA, USA aut Sanders John Naval Medical Research Center Detachment, Lima, Peru aut Riddle Mark Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, 20910, Silver Spring, MD, USA aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3602-3609 0163-2116 56:12<3602 2011 56 10620 https://doi.org/10.1007/s10620-011-1766-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1766-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Trivedi Kashyap Division of Gastroenterology, University of California, Irvine, Orange, CA, USA aut NATIONALLICENCE 700 1- Schlett Carey Uniformed Services University of the Health Sciences, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Tribble David Uniformed Services University of the Health Sciences, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Monteville Marshall Navy and Marine Corps Public Health Center, Norfolk, VA, USA aut NATIONALLICENCE 700 1- Sanders John Naval Medical Research Center Detachment, Lima, Peru aut NATIONALLICENCE 700 1- Riddle Mark Enteric Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, 20910, Silver Spring, MD, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3602-3609 0163-2116 56:12<3602 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer