caa a22 4500 445794666 CHVBK 20180317145120.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10620-011-1809-5 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1809-5 Severe Acute Pancreatitis During Pregnancy: Eleven Years Experience from a Surgical Intensive Care Unit [Elektronische Daten] [Yanxia Geng, Weiqin Li, Liqun Sun, Zhihui Tong, Ning Li, Jieshou Li] Objective: Acute pancreatitis during pregnancy is a rare and dangerous disease. This study attempts to present a comprehensive analysis of severe acute pancreatitis (SAP) during pregnancy and to identify the factors associated with poor outcomes. Methods: This study was a retrospective review of the medical records of SAP patients during pregnancy consecutively admitted into the Research Institute of General Surgery from 1999 to 2010. Results: Information was collected on presentation, management, and outcome. Eighteen patients were identified to have been diagnosed with SAP during pregnancy. Eleven patients (61.1%) were nulliparous; most attacks (88.9%) occurred during the third trimester. There were seven cases with preterm labor, six with fetal losses, and no maternal death. The etiology was biliary disease in seven patients (38.9%), hypertriglyceridemia in five patients (27.8%), both biliary and hypertriglyceridemia in four patients (22.2%), and idiopathic in two patients (11.1%). Patients with failure in more than one (≥2) organ were more likely to result in fetal loss (OR=25, P=0.016). Conclusions: SAP during pregnancy is predominantly biliary in etiology, but a significant proportion is caused by hypertriglyceridemia. Patients with failure in at least two organs result in relatively worse fetal outcomes. Springer Science+Business Media, LLC, 2011 Severe acute pancreatitis nationallicence Pregnancy nationallicence Hypertriglyceridemia nationallicence Fetal loss nationallicence Organ failure nationallicence Geng Yanxia Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Li Weiqin Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Sun Liqun Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Tong Zhihui Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Li Ning Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Li Jieshou Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3672-3677 0163-2116 56:12<3672 2011 56 10620 https://doi.org/10.1007/s10620-011-1809-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1809-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Geng Yanxia Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 700 1- Li Weiqin Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 700 1- Sun Liqun Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 700 1- Tong Zhihui Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 700 1- Li Ning Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 700 1- Li Jieshou Intensive Care Unit, Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, 305 Zhong Shan East Road, 210002, Nanjing, China aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3672-3677 0163-2116 56:12<3672 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer