caa a22 4500 445794771 CHVBK 20180317145121.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10620-011-1799-3 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1799-3 Curry Induces Acid Reflux and Symptoms in Gastroesophageal Reflux Disease [Elektronische Daten] [Lee Lim, Huiwen Tay, Khek Ho] Background: There are limited data on the effect of curry on gastroesophageal reflux disease (GERD). Our objective was to study the effects of curry on GERD. Methods: Symptomatic non-erosive gastroesophageal reflux disease (NERD) patients and healthy volunteers underwent ambulatory 24-h esophageal pH monitoring before consumption of either 400 or 800ml of curry; they were monitored for 3h thereafter for changes in esophageal pH and upper abdominal symptoms. Selected volunteers were monitored similarly after water ingestion. Results: In total, 25 NERD patients (23 males; mean age, 45years) and 19 volunteers (13 males; mean age, 22years) participated. In both patients and volunteers, curry ingestion induced more esophageal acid exposure than did ingestion of a similar volume of water. Curry induced significantly more esophageal acid exposure in NERD patients than in volunteers. Upper abdominal symptoms and esophageal acid exposure were more severe and persisted longer in patients than in volunteers. Conclusion: Curry induced more acid reflux and caused worse symptoms in patients with NERD than in healthy individuals. Patients with NERD should be advised to avoid curry ingestion. Springer Science+Business Media, LLC, 2011 Curry nationallicence Acid nationallicence Reflux nationallicence Symptoms nationallicence Lim Lee Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut Tay Huiwen Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut Ho Khek Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3546-3550 0163-2116 56:12<3546 2011 56 10620 https://doi.org/10.1007/s10620-011-1799-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1799-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lim Lee Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut NATIONALLICENCE 700 1- Tay Huiwen Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut NATIONALLICENCE 700 1- Ho Khek Department of Gastroenterology and Hepatology, National University Health System, Singapore, Singapore aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3546-3550 0163-2116 56:12<3546 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer