caa a22 4500 445794836 CHVBK 20180317145121.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10620-011-1798-4 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1798-4 Is It Worthwhile to Perform Capsule Endoscopy for Asymptomatic Patients with Positive Immunochemical Faecal Occult Blood Test? [Elektronische Daten] [Hideyuki Chiba, Masau Sekiguchi, Takafumi Ito, Yosuke Tsuji, Ken Ohata, Akiko Ohno, Shotaro Umezawa, Suguru Takeuchi, Kantaro Hisatomi, Takuma Teratani, Nobuyuki Matsuhashi, Hiroki Endo, Masahiko Inamori, Atsushi Nakajima] Background: The immunochemical faecal occult blood test (IFOBT) is widely performed for colorectal cancer screening, but the usefulness of IFOBT in the detection of disorders of the small intestine is unknown. The objective of this study was to investigate what proportion of IFOBT-positive subjects with negative colonoscopy and oesophagogastroduodenoscopy has pathologies of the small intestine detected by capsule endoscopy (CE). Methods: Between October 2008 and June 2010, asymptomatic IFOBT-positive patients with negative total colonoscopy and oesophagogastroduodenoscopy underwent CE. CE findings were classified into three categories: P0 (no abnormalities, or findings without potential for bleeding), P1 (findings with uncertain potential for bleeding), P2 and (findings with high potential for bleeding). Results: Fifty-three patients (37 males, 16 females; 52.1±13.0years) were included. There were no cases with P2, 19 cases with P1, and 34 cases with P0 (there were no abnormalities in 25 of 34 cases). As a result, lesions in the small intestine were detected in 28 cases. Additional examination was considered necessary for five patients after CE, but no abnormality was detected, and therapeutic intervention was not undertaken in any case. Caecal completion rate was 92.5%. Conclusions: No significant pathologies of the small intestine were detected in asymptomatic IFOBT-positive cases with negative colonoscopy and oesophagogastroduodenoscopy. CE is of limited use in asymptomatic patients with positive IFOBT. Springer Science+Business Media, LLC, 2011 Capsule endoscopy nationallicence Immunochemical faecal occult blood tests nationallicence Occult obscure gastrointestinal bleeding nationallicence Chiba Hideyuki Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Sekiguchi Masau Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Ito Takafumi Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Tsuji Yosuke Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Ohata Ken Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Ohno Akiko Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Umezawa Shotaro Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Takeuchi Suguru Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Hisatomi Kantaro Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Teratani Takuma Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Matsuhashi Nobuyuki Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut Endo Hiroki Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut Inamori Masahiko Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut Nakajima Atsushi Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3459-3462 0163-2116 56:12<3459 2011 56 10620 https://doi.org/10.1007/s10620-011-1798-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1798-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chiba Hideyuki Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Sekiguchi Masau Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Ito Takafumi Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuji Yosuke Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Ohata Ken Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Ohno Akiko Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Umezawa Shotaro Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Takeuchi Suguru Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Hisatomi Kantaro Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Teratani Takuma Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Matsuhashi Nobuyuki Department of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, 141-8625, Shinagawa-Ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Endo Hiroki Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut NATIONALLICENCE 700 1- Inamori Masahiko Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut NATIONALLICENCE 700 1- Nakajima Atsushi Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, 236-0004, Kanazawa-Ku, Yokohama, Japan aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/12(2011-12-01), 3459-3462 0163-2116 56:12<3459 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer