caa a22 4500 445795522 CHVBK 20180317145123.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10620-011-1700-4 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1700-4 Is the Colonic Response to Food Different in IBS in Contrast to Simple Constipation or Diarrhea Without Abdominal Pain? [Elektronische Daten] [Michel Bouchoucha, Ghislain Devroede, Jean-Jacques Raynaud, Cyriaque Bon, Bakhtiar Bejou, Robert Benamouzig] Background: Colonic response to food (CRF) is abnormal in irritable bowel syndrome (IBS) patients. Aims: The aim of this study was to compare CRF in patients who complain of abnormal defecation pattern according to the presence or absence of abdominal pain. Methods: One hundred forty-nine patients and 50 controls were studied: 96 IBS patients (46 IBS-C, 13 IBS-D, 15 IBS-M, and 22 IBS-U not included), 43 patients with functional constipation (group C) and ten with functional diarrhea (group D). Clinical evaluation and visual analog scales about four items (constipation, diarrhea, abdominal bloating and abdominal pain) were filled by all subjects. Colonic transit time (CTT) was measured in fasting conditions and after eating a standard 1,000-cal test meal. CRF was quantified by calculating the variation in number of markers between the two films. Results: The frequency of meal-related symptoms did not vary among the different groups of patients but was significantly higher than in controls. Compared to IBS-C patients, constipated patients of the group C had longer total and segmental colonic transit time, and compared to IBS-D patients, diarrheic patients of the group D had shorter oro-anal and segmental colonic transit time except in the recto-sigmoid area. CRF was different in patients and controls, and differed between IBS and non IBS patients with similar transit abnormalities. Stool output was greater in patients of the group D than in patients of the IBS-D group. Conclusion: The different subgroups of IBS patients have different CRF patterns, distinct from subjects with constipation and diarrhea, but without abdominal pain. Springer Science+Business Media, LLC, 2011 IBS nationallicence CRF nationallicence Abdominal pain nationallicence Diarrhea nationallicence Constipation nationallicence Meal nationallicence CRF : Colonic response to food nationallicence IBS : Irritable bowel syndrome nationallicence Bouchoucha Michel Université Paris V René Descartes 15, rue de l'école de médecine, 75270, Paris Cedex 06, France aut Devroede Ghislain Département de Chirurgie, Faculté de Médecine, Université de Sherbrooke, Sherbrooke, QC, Canada aut Raynaud Jean-Jacques Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut Bon Cyriaque Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut Bejou Bakhtiar Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut Benamouzig Robert Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2947-2956 0163-2116 56:10<2947 2011 56 10620 https://doi.org/10.1007/s10620-011-1700-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1700-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bouchoucha Michel Université Paris V René Descartes 15, rue de l'école de médecine, 75270, Paris Cedex 06, France aut NATIONALLICENCE 700 1- Devroede Ghislain Département de Chirurgie, Faculté de Médecine, Université de Sherbrooke, Sherbrooke, QC, Canada aut NATIONALLICENCE 700 1- Raynaud Jean-Jacques Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut NATIONALLICENCE 700 1- Bon Cyriaque Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut NATIONALLICENCE 700 1- Bejou Bakhtiar Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut NATIONALLICENCE 700 1- Benamouzig Robert Service de Gastroentérologie, CEFRED (centre d'exploration fonctionnelle et de rééducation digestive), Hôpital Avicenne, 125, rue de Stalingrad, 93009, Bobigny Cedex, France aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2947-2956 0163-2116 56:10<2947 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer