caa a22 4500 445795557 CHVBK 20180317145123.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10620-011-1679-x doi (NATIONALLICENCE)springer-10.1007/s10620-011-1679-x Lifestyle Change Influences on GERD in Japan: A Study of Participants in a Health Examination Program [Elektronische Daten] [Tetsuya Murao, Kouichi Sakurai, Syuuichi Mihara, Toru Marubayashi, Yoshitaka Murakami, Yutaka Sasaki] Background: Though gastroesophageal reflux disease (GERD) has been a prevalent disease in Western countries, the incidence of GERD has only just started to increase in Japan. Aim: The aim of this study was to determine which lifestyle factors may be associated with GERD in Japan. Methods: A total of 2,853 participants who took part in a health examination program between July 2004 and March 2005 were enrolled. GERD symptoms were assessed using the Japanese version of the Carlsson-Dent self-administered questionnaire (QUEST). The GERD group consisted of participants with a QUEST score ≥6 and/or endoscopic findings. The GERD group was divided into asymptomatic ERD (erosive reflux disease with no symptoms), symptomatic ERD (erosive reflux disease with symptoms) and NERD (non-erosive reflux disease) groups. Associated factors for these diseases were analyzed by logistic regression analysis. Results: GERD was diagnosed in 667 (23.4%) participants. Among the subjects placed in the GERD group, asymptomatic ERD, symptomatic ERD and NERD were diagnosed in 232 (8.1%), 91 (3.2%) and 344 (12.1%) participants, respectively. Factors associated with GERD included a high BMI (body mass index), hiatus hernia, fewer hours of sleep, lack of exercise, and drinking green tea. Conclusions: Relationships between lifestyle, gender and GERD were investigated in the present study. Both lifestyle improvements and consideration of gender differences can be used to help prevent GERD development. The Author(s), 2011 Gastroesophageal reflux disease (GERD) nationallicence Japanese nationallicence Lifestyle nationallicence Gender nationallicence Murao Tetsuya Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut Sakurai Kouichi Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut Mihara Syuuichi Japanese Red Cross Kumamoto Health Care Center, 1-1 Nagamineminami, 861-8528, Kumamoto City, Kumamoto, Japan aut Marubayashi Toru Japanese Red Cross Kumamoto Health Care Center, 1-1 Nagamineminami, 861-8528, Kumamoto City, Kumamoto, Japan aut Murakami Yoshitaka Department of Medical Statistics, Shiga University of Medical Science, Seta Tsukinowa-cho, 520-2192, Otsu City, Shiga, Japan aut Sasaki Yutaka Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2857-2864 0163-2116 56:10<2857 2011 56 10620 https://doi.org/10.1007/s10620-011-1679-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1679-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murao Tetsuya Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut NATIONALLICENCE 700 1- Sakurai Kouichi Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut NATIONALLICENCE 700 1- Mihara Syuuichi Japanese Red Cross Kumamoto Health Care Center, 1-1 Nagamineminami, 861-8528, Kumamoto City, Kumamoto, Japan aut NATIONALLICENCE 700 1- Marubayashi Toru Japanese Red Cross Kumamoto Health Care Center, 1-1 Nagamineminami, 861-8528, Kumamoto City, Kumamoto, Japan aut NATIONALLICENCE 700 1- Murakami Yoshitaka Department of Medical Statistics, Shiga University of Medical Science, Seta Tsukinowa-cho, 520-2192, Otsu City, Shiga, Japan aut NATIONALLICENCE 700 1- Sasaki Yutaka Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, 860-8556, Kumamoto City, Kumamoto, Japan aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2857-2864 0163-2116 56:10<2857 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer