caa a22 4500 445795573 CHVBK 20180317145123.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10620-011-1773-0 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1773-0 CT-Enterography May Identify Small Bowel Tumors Not Detected by Capsule Endoscopy: Eight Years Experience at Mayo Clinic Rochester [Elektronische Daten] [Fayaz Hakim, Jeffrey Alexander, James Huprich, Madhusudan Grover, Felicity Enders] Background: Capsule endoscopy (CE) is widely accepted as the preferred diagnostic test in the evaluation of small bowel diseases. However, small bowel tumors (SBT) are sometimes missed by CE. Preliminary studies suggest that CT-enterography (CTE) may play a role in detecting SBT. Aims: The purpose of this study was to compare the performance of CE and CTE in detecting SBT Methods: This was a single center, retrospective study. Patients treated at the Mayo Clinic Rochester between January 2000 and December 2008 with a discharge diagnosis of SBT and negative initial esophagogastroduodenoscopy (EGD) and colonoscopy were identified through a search of the electronic medical records. Among 103 identified patients, 41 had undergone CE, CTE or both, and comprised our study group. The exact binomial sensitivity of CE and CTE in detecting SBT was calculated. Demographic characteristics, clinical presentation, results of diagnostic tests, and tumor characteristics were recorded for each patient. Results: CTE and CE detected 38/41 (sensitivity 92.7%; 95% CI 80.1-98.5) and 8/27 (sensitivity 29.6%; 95% CI 13.8-50.2) of the SBT identified at Mayo Clinic Rochester, respectively. Seventeen patients had both CTE and CE. In this subgroup of patients, CTE detected SBT in 16/17 (sensitivity 94.1; 95% CI 72.7-99.9) and CE in 6/17 (sensitivity 35.3%; 95% CI 13.3-59). The matched paired difference in the sensitivity of two techniques in detecting SBT was statistically significant (P=0.004). Conclusion: CTE may identify SBT not diagnosed by CE. Springer Science+Business Media, LLC, 2011 Small bowel tumors nationallicence Capsule endoscopy nationallicence CT-enterography nationallicence Hakim Fayaz General Internal Medicine, Mayo Clinic, Rochester, MN, USA aut Alexander Jeffrey Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, 9 East, 100 First street SW, 55905, Rochester, MN, USA aut Huprich James Department of Radiology, Mayo Clinic, Rochester, MN, USA aut Grover Madhusudan Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, 9 East, 100 First street SW, 55905, Rochester, MN, USA aut Enders Felicity Department of Biostatistics, Mayo Clinic, Rochester, MN, USA aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2914-2919 0163-2116 56:10<2914 2011 56 10620 https://doi.org/10.1007/s10620-011-1773-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1773-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hakim Fayaz General Internal Medicine, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Alexander Jeffrey Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, 9 East, 100 First street SW, 55905, Rochester, MN, USA aut NATIONALLICENCE 700 1- Huprich James Department of Radiology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Grover Madhusudan Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, 9 East, 100 First street SW, 55905, Rochester, MN, USA aut NATIONALLICENCE 700 1- Enders Felicity Department of Biostatistics, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2914-2919 0163-2116 56:10<2914 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer