caa a22 4500 445795735 CHVBK 20180317145124.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10620-011-1693-z doi (NATIONALLICENCE)springer-10.1007/s10620-011-1693-z Evaluation of Different Bowel Preparations for Small Bowel Capsule Endoscopy: A Prospective, Randomized, Controlled Study [Elektronische Daten] [Vicente Pons Beltrán, Begoña González Suárez, Cecilia González Asanza, Enrique Pérez-Cuadrado, Servando Fernández Diez, Iñaqui Fernández-Urién, Alfredo Mata Bilbao, Jorge Espinós Pérez, Maria Pérez Grueso, Lidia Argüello Viudez, Julio Valle Muñoz, Fernando Carballo Alvarez, Miguel Muñoz-Navas, Jose Llach Vila, Juan Ramírez Armengol, Joaquin Balanzó Tintoré, Teresa Sala Felis, Pedro Menchen Fernández-Pacheco] Background and Study Aims: To obtain an adequate view of the whole small intestine during capsule endoscopy (CE) a clear liquid diet and overnight fasting is recommended. However, intestinal content can hamper vision in spite of these measures. Our aim was to evaluate tolerance and degree of intestinal cleanliness during CE following three types of bowel preparation. Patients and Methods: This was a prospective, multicenter, randomized, controlled study. Two-hundred ninety-one patients underwent one of the following preparations: 4L of clear liquids (CL) (group A; 92 patients); 90mL of aqueous sodium phosphate (group B; 89 patients); or 4L of a polyethylene glycol electrolyte solution (group C; 92 patients). The degree of cleanliness of the small bowel was classified by blinded examiners according to four categories (excellent, good, fair or poor). The degree of patient satisfaction, gastric and small bowel transit times, and diagnostic yield were measured. Results: The degree of cleanliness did not differ significantly between the groups (P=0.496). Interobserver concordance was fair (k=0.38). No significant differences were detected between the diagnostic yields of the CE (P=0.601). Gastric transit time was 35.7±3.7min (group A), 46.1±8.6min (group B) and 34.6±5.0min (group C) (P=0.417). Small-intestinal transit time was 276.9±10.7min (group A), 249.7±13.1min (group B) and 245.6±11.6min (group C) (P=0.120). CL was the best tolerated preparation. Compliance with the bowel preparation regimen was lowest in group C (P=0.008). Conclusions: A clear liquid diet and overnight fasting is sufficient to achieve an adequate level of cleanliness and is better tolerated by patients than other forms of preparation. Springer Science+Business Media, LLC, 2011 Capsule endoscopy nationallicence Bowel preparation nationallicence Polyethylene glycol electrolyte solution nationallicence Aqueous sodium phosphate nationallicence CE : Capsule endoscopy nationallicence ASP : Aqueous sodium phosphate nationallicence PEG : Polyethylene glycol electrolyte solution nationallicence CL : Clear liquids nationallicence Pons Beltrán Vicente Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut González Suárez Begoña Gastroenterology Unit, Sant Pau Hospital, Barcelona, Spain aut González Asanza Cecilia Gastroenterology Unit, Gregorio Marañón Hospital, Madrid, Spain aut Pérez-Cuadrado Enrique Gastroenterology Unit, Morales Meseguer Hospital, Murcia, Spain aut Fernández Diez Servando Gastroenterology Unit, Clínic Hospital, Madrid, Spain aut Fernández-Urién Iñaqui Gastroenterology Unit, University Clínic of Navarra, Pamplona, Spain aut Mata Bilbao Alfredo Gastroenterology Unit, Clínic Hospital, Barcelona, Spain aut Espinós Pérez Jorge Gastroenterology Unit, Teknon Clínic, Barcelona, Spain aut Pérez Grueso Maria Gastroenterology Unit, Virgen de la Salud Hospital, Toledo, Spain aut Argüello Viudez Lidia Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut Valle Muñoz Julio Gastroenterology Unit, Virgen de la Salud Hospital, Toledo, Spain aut Carballo Alvarez Fernando Gastroenterology Unit, Morales Meseguer Hospital, Murcia, Spain aut Muñoz-Navas Miguel Gastroenterology Unit, University Clínic of Navarra, Pamplona, Spain aut Llach Vila Jose Gastroenterology Unit, Clínic Hospital, Barcelona, Spain aut Ramírez Armengol Juan Gastroenterology Unit, Clínic Hospital, Madrid, Spain aut Balanzó Tintoré Joaquin Gastroenterology Unit, Sant Pau Hospital, Barcelona, Spain aut Sala Felis Teresa Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut Menchen Fernández-Pacheco Pedro Gastroenterology Unit, Gregorio Marañón Hospital, Madrid, Spain aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2900-2905 0163-2116 56:10<2900 2011 56 10620 https://doi.org/10.1007/s10620-011-1693-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1693-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pons Beltrán Vicente Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut NATIONALLICENCE 700 1- González Suárez Begoña Gastroenterology Unit, Sant Pau Hospital, Barcelona, Spain aut NATIONALLICENCE 700 1- González Asanza Cecilia Gastroenterology Unit, Gregorio Marañón Hospital, Madrid, Spain aut NATIONALLICENCE 700 1- Pérez-Cuadrado Enrique Gastroenterology Unit, Morales Meseguer Hospital, Murcia, Spain aut NATIONALLICENCE 700 1- Fernández Diez Servando Gastroenterology Unit, Clínic Hospital, Madrid, Spain aut NATIONALLICENCE 700 1- Fernández-Urién Iñaqui Gastroenterology Unit, University Clínic of Navarra, Pamplona, Spain aut NATIONALLICENCE 700 1- Mata Bilbao Alfredo Gastroenterology Unit, Clínic Hospital, Barcelona, Spain aut NATIONALLICENCE 700 1- Espinós Pérez Jorge Gastroenterology Unit, Teknon Clínic, Barcelona, Spain aut NATIONALLICENCE 700 1- Pérez Grueso Maria Gastroenterology Unit, Virgen de la Salud Hospital, Toledo, Spain aut NATIONALLICENCE 700 1- Argüello Viudez Lidia Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut NATIONALLICENCE 700 1- Valle Muñoz Julio Gastroenterology Unit, Virgen de la Salud Hospital, Toledo, Spain aut NATIONALLICENCE 700 1- Carballo Alvarez Fernando Gastroenterology Unit, Morales Meseguer Hospital, Murcia, Spain aut NATIONALLICENCE 700 1- Muñoz-Navas Miguel Gastroenterology Unit, University Clínic of Navarra, Pamplona, Spain aut NATIONALLICENCE 700 1- Llach Vila Jose Gastroenterology Unit, Clínic Hospital, Barcelona, Spain aut NATIONALLICENCE 700 1- Ramírez Armengol Juan Gastroenterology Unit, Clínic Hospital, Madrid, Spain aut NATIONALLICENCE 700 1- Balanzó Tintoré Joaquin Gastroenterology Unit, Sant Pau Hospital, Barcelona, Spain aut NATIONALLICENCE 700 1- Sala Felis Teresa Gastroenterology Unit, La Fe University and Polytechnic Hospital, Valencia, Spain aut NATIONALLICENCE 700 1- Menchen Fernández-Pacheco Pedro Gastroenterology Unit, Gregorio Marañón Hospital, Madrid, Spain aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/10(2011-10-01), 2900-2905 0163-2116 56:10<2900 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer