caa a22 4500 445795816 CHVBK 20180317145124.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10620-011-1635-9 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1635-9 Gastric Emptying of Solids and Liquids for Evaluation for Gastroparesis [Elektronische Daten] [Priyanka Sachdeva, Nidhi Malhotra, Murali Pathikonda, Umar Khayyam, Robert Fisher, Alan Maurer, Henry Parkman] Background: Gastric emptying scintigraphy (GES) of solids is typically used to evaluate for gastroparesis. Aims: The purpose of this study was to determine the value of simultaneously measuring gastric emptying of liquids and solids for assessing patients for delayed gastric emptying. Methods: A total of 596 patients at our institution from September 2007 to January 2010 underwent GES with assessment of both solid and liquid gastric emptying. An EggBeaters® with jam sandwich meal radiolabeled with Tc-99m was used for solid GES and water radiolabeled with In-111 for liquid GES. Results: Inclusion criteria (no medications affecting gastric motility in 48h prior to test; no prior gastric surgery) was met by 449 patients. Liquid gastric emptying was significantly correlated to solid gastric emptying: 30min (r=0.652, P<0.001), 60min (r=0.624, P<0.001) and 120min (r=0.766, P<0.001). Interestingly, 60 patients, of which 57 were nondiabetic, had normal solid GES but delayed liquid emptying and represented 26% of the 228 patients with normal solid GES. Gastric retention of solids was mildly correlated with nausea, vomiting, loss of appetite, early satiety and feeling excessively full after meals. Gastric emptying of liquids was associated with early satiety and loss of appetite. Conclusions: Gastric emptying of liquids correlates well with gastric emptying of solids. When evaluating patients for gastroparesis, assessment of gastric emptying of liquids in addition to solids may help identify additional patients with delayed gastric emptying, particularly non-diabetic patients where 26% with normal solid emptying may have delayed emptying of liquids. Symptoms of gastroparesis, however, are primarily associated with delayed gastric emptying of solids. Springer Science+Business Media, LLC, 2011 Gastric emptying scintigraphy nationallicence Gastroparesis nationallicence Nausea nationallicence Vomiting nationallicence Sachdeva Priyanka Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Malhotra Nidhi Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Pathikonda Murali Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Khayyam Umar Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Fisher Robert Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Maurer Alan Department of Radiology, Temple University School of Medicine, Philadelphia, PA, USA aut Parkman Henry Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/4(2011-04-01), 1138-1146 0163-2116 56:4<1138 2011 56 10620 https://doi.org/10.1007/s10620-011-1635-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1635-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sachdeva Priyanka Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Malhotra Nidhi Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Pathikonda Murali Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Khayyam Umar Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Fisher Robert Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Maurer Alan Department of Radiology, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Parkman Henry Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/4(2011-04-01), 1138-1146 0163-2116 56:4<1138 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer