caa a22 4500 445796138 CHVBK 20180317145125.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10620-010-1553-2 doi (NATIONALLICENCE)springer-10.1007/s10620-010-1553-2 Sonnenberg Amnon The Oregon Health and Science University, Portland, OR, USA aut Time Trends of Mortality from Gastric Cancer in Europe [Elektronische Daten] [Amnon Sonnenberg] Background: The time trends of gastric and duodenal ulcer disease are shaped by a birth-cohort phenomenon. Aims: The aim of this study was to assess the extent by which a birth-cohort phenomenon also affected the long-term time trends of gastric cancer among different European countries. Methods: Mortality data from France, Germany, Netherlands, Scotland, Spain, and Sweden of the past 56-85years were analyzed. The age-specific death rates were plotted against the period of death as period-age contours and against the period of birth as cohort-age contours. Results: The long-term time trends of gastric cancer mortality were found to have risen among generations born during the 18th century until the mid-19th century and then to have declined in all subsequent generations. The rise and fall of gastric cancer preceded similar birth-cohort patterns of gastric and duodenal ulcer by about 10-30years. With the exception of gastric cancer in Germany, similar birth-cohort phenomena were found in all countries, as well as in men and women. Conclusions: The time trends of mortality from gastric cancer and peptic are shaped by birth-cohort patterns that have affected all countries of Europe. It remains an enigma why mortality associated with gastric cancer and peptic ulcer suddenly started to rise within a short time period during the 19th century. Springer Science+Business Media, LLC (Outside the USA), 2011 Birth-cohorts nationallicence Duodenal ulcer nationallicence Epidemiology nationallicence Gastric cancer nationallicence Gastric ulcer nationallicence Helicobacter pylori nationallicence Mortality nationallicence Time trends nationallicence GCA : Gastric cancer nationallicence GU : Gastric ulcer nationallicence DU : Duodenal ulcer nationallicence ICD : International Classification of Diseases nationallicence SCMR : Standardized cohort mortality ratio nationallicence Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/4(2011-04-01), 1112-1118 0163-2116 56:4<1112 2011 56 10620 https://doi.org/10.1007/s10620-010-1553-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-010-1553-2 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sonnenberg Amnon The Oregon Health and Science University, Portland, OR, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/4(2011-04-01), 1112-1118 0163-2116 56:4<1112 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer