caa a22 4500 445796545 CHVBK 20180317145127.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10620-011-1608-z doi (NATIONALLICENCE)springer-10.1007/s10620-011-1608-z A Comparative Study of Endoscopic Ultrasound Guided Fine Needle Aspiration With and Without a Stylet [Elektronische Daten] [Sachin Wani, Neil Gupta, Srinivas Gaddam, Vikas Singh, Ozlem Ulusarac, Maria Romanas, Ajay Bansal, Prateek Sharma, Mojtaba Olyaee, Amit Rastogi] Background: Despite lack of evidence, use of a stylet during endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is assumed to improve the quality and diagnostic yield of specimens. Aim: The purpose of this study was to compare EUS-FNA specimens obtained with stylet (S+) and without stylet (S−) for: (i) cellularity, contamination, adequacy, and amount of blood and (ii) diagnostic yield of malignancy. Methods: Patients who underwent EUS-FNA of solid lesions by two experienced endosonographers at a tertiary referral center using a 22-gauge FNA needle with suction were included. Stylet was used for all EUS-FNA procedures performed between January 2006 and September 2007 and no stylet was used between October 2007 and April 2009 allowing comparison between the two techniques. Cytology slides were retrieved, de-identified and evaluated by two experienced cytopathologists blinded to FNA technique. Slides were evaluated for cellularity, degree of contamination, adequacy, amount of blood and cytologic diagnosis. Fisher's exact and unpaired t-test were used for comparative analysis. Results: A total of 162 patients with 228 lesions were included. FNA of 106 and 122 lesions each was performed in the S+and S−groups, respectively. FNA sites included pancreas [41 (18%)], lymph node [125 (55%)], liver [20 (9%)], adrenal [21 (9%)] and others [21 (9%)]. No significant differences in the cellularity (P=0.37), contamination (P=0.18), significant blood (P=0.42) and adequacy of specimen (P=0.45) were found between S+and S−specimens. There was no statistically significant difference in the diagnostic yield of malignant lesions (P=0.48). Conclusions: The use of stylet during FNA does not appear to confer any advantage with regards to the adequacy of specimen or diagnostic yield of malignancy. Springer Science+Business Media, LLC, 2011 Endoscopic ultrasound nationallicence Fine needle aspiration nationallicence Stylet nationallicence Wani Sachin Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Gupta Neil Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Gaddam Srinivas Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Singh Vikas Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Ulusarac Ozlem Division of Gastroenterology and Hepatology, Department of Pathology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Romanas Maria Division of Gastroenterology and Hepatology, Department of Pathology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Bansal Ajay Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Sharma Prateek Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Olyaee Mojtaba Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Rastogi Amit Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/8(2011-08-01), 2409-2414 0163-2116 56:8<2409 2011 56 10620 https://doi.org/10.1007/s10620-011-1608-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1608-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wani Sachin Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Gupta Neil Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Gaddam Srinivas Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Singh Vikas Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Ulusarac Ozlem Division of Gastroenterology and Hepatology, Department of Pathology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Romanas Maria Division of Gastroenterology and Hepatology, Department of Pathology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Bansal Ajay Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Sharma Prateek Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Olyaee Mojtaba Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 700 1- Rastogi Amit Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E. Linwood Blvd, 64128-2295, Kansas City, MO, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/8(2011-08-01), 2409-2414 0163-2116 56:8<2409 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer