caa a22 4500 445796561 CHVBK 20180317145127.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10620-011-1741-8 doi (NATIONALLICENCE)springer-10.1007/s10620-011-1741-8 Characteristics of Small Bowel Tumors Detected by Double Balloon Endoscopy [Elektronische Daten] [Hiroya Imaoka, Naoyuki Higaki, Teru Kumagi, Jirou Miyaike, Masaki Ohmoto, Kazuhiko Yamauchi, Takatoshi Murakami, Hidehiro Murakami, Yoshiou Ikeda, Tomoyuki Yokota, Naozumi Shibata, Tomoyuki Ninomiya, Masanori Abe, Yoichi Hiasa, Bunzo Matsuura, Morikazu Onji, Masakichi Umeda, Norio Horiike] Background: A few reports suggest that the emergence of double balloon endoscopy (DBE) has likely changed the clinical picture of small bowel tumors (SBTs). Aim: To further clarify the characteristics of SBTs detected by DBE. Methods: A retrospective chart review was conducted in 227 patients who had undergone DBE. Results: The SBT group contained more symptomatic patients than the non-SBT group (90% vs. 49%, P<0.0005) with a significantly higher rate of gastrointestinal symptoms at presentation (72% vs. 33%, P<0.005). Twenty patients (8.8%) were eventually diagnosed with SBT, and their indications for DBE were obscure gastrointestinal bleeding (n=5), abdominal pain (n=5), abdominal fullness (n=5), vomiting (n=2), and diarrhea (n=1). Tumors were located in the jejunum in 14 patients (70%) and in the ileum in 6 (30%). A final histological diagnosis was assigned to all 20 patients: primary adenocarcinoma (n=8, 40%), malignant lymphoma (n=5, 25%), metastatic cancer (n=4, 20%), gastrointestinal stromal tumor (n=1, 5%), carcinoid tumor (n=1, 5%) and inflammatory fibroid polyp (n=1, 5%). Stenosis or ulceration were the most frequently observed endoscopic findings (n=13, 65%). All primary adenocarcinomas and three of four (75%) metastatic cancers showed stenosis or ulceration. Three of five (60%) malignant lymphomas showed multiple lymphomatous polyps. All patients but one underwent surgical resection or chemotherapy or both. Conclusion: DBE is a safe and useful procedure that enables a precise diagnosis of SBTs. Springer Science+Business Media, LLC, 2011 Small bowel tumors nationallicence Double balloon endoscopy nationallicence Presentation nationallicence Tumor location nationallicence Endoscopic findings nationallicence Final histological diagnosis nationallicence CE : Capsule endoscopy nationallicence DBE : Double balloon endoscopy nationallicence GISTs : Gastrointestinal stromal tumors nationallicence MLP : Multiple lymphomatous polyposis nationallicence OGIB : Obscure gastrointestinal bleeding nationallicence SBT : Small bowel tumor nationallicence SMT : Submucosal tumor nationallicence Imaoka Hiroya Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Higaki Naoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Kumagi Teru Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Miyaike Jirou Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Ohmoto Masaki Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Yamauchi Kazuhiko Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Murakami Takatoshi Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Murakami Hidehiro Endoscopy Center, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Ikeda Yoshiou Endoscopy Center, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Yokota Tomoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Shibata Naozumi Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Ninomiya Tomoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Abe Masanori Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Hiasa Yoichi Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Matsuura Bunzo Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Onji Morikazu Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut Umeda Masakichi Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Horiike Norio Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/8(2011-08-01), 2366-2371 0163-2116 56:8<2366 2011 56 10620 https://doi.org/10.1007/s10620-011-1741-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-011-1741-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Imaoka Hiroya Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Higaki Naoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Kumagi Teru Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Miyaike Jirou Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Ohmoto Masaki Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Yamauchi Kazuhiko Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Murakami Takatoshi Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Murakami Hidehiro Endoscopy Center, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Ikeda Yoshiou Endoscopy Center, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Yokota Tomoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Shibata Naozumi Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Ninomiya Tomoyuki Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Abe Masanori Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Hiasa Yoichi Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Matsuura Bunzo Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Onji Morikazu Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, 791-0295, Shitsukawa, Toon, Ehime, Japan aut NATIONALLICENCE 700 1- Umeda Masakichi Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 700 1- Horiike Norio Internal Medicine, Saiseikai Imabari Hospital, 799-1592, Kitamura, Imabari, Ehime, Japan aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/8(2011-08-01), 2366-2371 0163-2116 56:8<2366 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer