caa a22 4500 445797088 CHVBK 20180317145129.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s10620-010-1427-7 doi (NATIONALLICENCE)springer-10.1007/s10620-010-1427-7 Long-Term Recurrence Rates Following Dilation of Symptomatic Schatzki Rings [Elektronische Daten] [Michaela Müller, Ines Gockel, Jochem König, Kathrin Kuhr, Volker Eckardt] Background and Aims: This study investigated the long-term clinical course of patients with Schatzki rings, who were treated by single bougie dilation. Furthermore, it analyzed possible predictors for the time of recurrence. Patients and Methods: A total of 133 patients (100 males, 33 females) with a mean age of 57±14.6years who were treated by single dilation with the use of Maloney bougies without the aid of fluoroscopy were prospectively registered and followed-up for a mean duration of 58.3months (range 12-240months). Duration of remission was evaluated by Kaplan-Meier estimates with regard to recurrence. Log-rank test was performed to analyze possible predictors for the time to second dilation (recurrence). Results: No complications occurred and all patients were symptom-free at the first follow-up examination 4weeks after dilation. However, later on, 73 patients required a second dilation. The estimate remission rates were 63.8% (95% CI: 55.6-72.0%) after 2years, 44.3% (95% CI: 35.4-53.4%) after 5years, and 39.9% (95% CI: 30.5-49.3%) after 10years. Neither the initial morphological findings, nor age or gender determined the need for repeated dilation. Only patients treated with a large bougie diameter (≥52F) seemed to have a tendency for a longer time until symptomatic recurrence. Conclusions: Single dilation of symptomatic Schatzki rings is a safe and effective therapy. However, more than half of the patients will need a second treatment. Recurrences are unrelated to initial morphological findings, age, or gender. Only the treatment with a large bougie diameter (≥52F) showed a tendency for a longer time of remission. Springer Science+Business Media, LLC, 2010 Schatzki ring nationallicence Single dilation nationallicence Long-term remission nationallicence Predictors of recurrence nationallicence Müller Michaela Department of Gastroenterology, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191, Wiesbaden, Germany aut Gockel Ines Department of General and Abdominal Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut König Jochem Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut Kuhr Kathrin Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut Eckardt Volker Department of Gastroenterology, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191, Wiesbaden, Germany aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/5(2011-05-01), 1432-1437 0163-2116 56:5<1432 2011 56 10620 https://doi.org/10.1007/s10620-010-1427-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-010-1427-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Müller Michaela Department of Gastroenterology, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191, Wiesbaden, Germany aut NATIONALLICENCE 700 1- Gockel Ines Department of General and Abdominal Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- König Jochem Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Kuhr Kathrin Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Eckardt Volker Department of Gastroenterology, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191, Wiesbaden, Germany aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/5(2011-05-01), 1432-1437 0163-2116 56:5<1432 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer