caa a22 4500 445797576 CHVBK 20180317145130.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10620-010-1289-z doi (NATIONALLICENCE)springer-10.1007/s10620-010-1289-z Narrow Band Imaging to Detect Residual or Recurrent Neoplastic Tissue During Surveillance Endoscopy [Elektronische Daten] [Jason Rogart, Harry Aslanian, Uzma Siddiqui] Background: There is little data on the prevalence of residual neoplastic tissue or the rate of endoscopically detected recurrence in patients with prior surgical or endoscopic resection of advanced neoplasia. Aims: To compare standard white light with NBI for both the detection, as well as the differentiation, of residual or recurrent neoplastic tissue during real-time endoscopy. Methods: A prospective study of 46 consecutive patients undergoing surveillance colonoscopy or upper endoscopy was conducted. Prior resection sites were examined first with white light and then with NBI. Main outcome measurements included the number of distinct lesions identified with white light, the number of additional lesions identified with NBI, and the overall accuracy of endoscopic diagnosis using white light alone or with NBI. Results: Sixty discrete lesions were identified, 43 with white light alone, and an additional 17 with NBI. NBI identified more lesions per patient than white light alone (mean 1.33 vs. 0.96, p<0.05) and there was a trend towards increased detection of neoplastic lesions. Recurrent/residual neoplasia was present in 14 patients (30%) and there was a trend towards increased detection with the addition of NBI. About 63% of lesions identified with white light appeared more extensive when examined with NBI. The diagnostic accuracy in predicting histology was equivalent for NBI and white light (87 vs. 88%), though there was a trend towards higher sensitivity for neoplastic lesions with NBI (88 vs. 69%, p=0.16). Conclusions: A substantial number of patients undergoing surveillance endoscopy had residual or recurrent neoplastic tissue identified at the prior resection site. As NBI detected additional neoplastic lesions as well as demonstrated that lesions detected with white light were more extensive, adjunctive use of NBI for examining post-endoscopy resection sites should be studied in future, larger studies. Springer Science+Business Media, LLC, 2010 Narrow band imaging nationallicence Endoscopy nationallicence Gastrointestinal neoplasms nationallicence Colorectal neoplasms nationallicence Rogart Jason Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut Aslanian Harry Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut Siddiqui Uzma Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/2(2011-02-01), 472-478 0163-2116 56:2<472 2011 56 10620 https://doi.org/10.1007/s10620-010-1289-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10620-010-1289-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rogart Jason Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut NATIONALLICENCE 700 1- Aslanian Harry Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut NATIONALLICENCE 700 1- Siddiqui Uzma Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, 333 Cedat St., 1080 LMP, 06520, New Haven, CT, USA aut NATIONALLICENCE 773 0- Digestive Diseases and Sciences Springer US; http://www.springer-ny.com 56/2(2011-02-01), 472-478 0163-2116 56:2<472 2011 56 10620 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer