caa a22 4500 445802308 CHVBK 20180317145145.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10337-010-1817-1 doi (NATIONALLICENCE)springer-10.1007/s10337-010-1817-1 On-Column Preconcentration of Anti-Inflammatory Drugs in River Water by Anion-Selective Exhaustive Injection-Sweeping-MEKC [Elektronische Daten] [Irene Maijó, Francesc Borrull, Carme Aguilar, Marta Calull] A high-sensitivity on-column preconcentration method, anion selective exhaustive injection (ASEI)-sweeping in micellar electrokinetic capillary chromatography (MEKC) has been developed for the analysis of non-steroidal anti-inflammatory drugs (NSAIDs): diclofenac sodium, ibuprofen, fenoprofen, naproxen, and ketoprofen in water samples. To achieve the best results of the ASEI-sweeping-MEKC method, conditions which affected preconcentration were examined, including the sodium dodecyl sulfate concentration, composition of the sample matrix, composition and injection length of the water plug, the concentration and the injection length of the high-conductivity buffer, and finally the sample injection time. Under the optimum stacking conditions the method was validated for the determination of the studied NSAIDs in river water samples with limits of detection ranging between 29 and 58ngmL−1, and without any previous sample pretreatment. Springer-Verlag, 2011 Micellar electrokinetic capillary chromatography nationallicence Anion-selective exhaustive injection nationallicence Sweeping nationallicence River water nationallicence Non-steroidal anti-inflammatory drugs nationallicence Maijó Irene Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut Borrull Francesc Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut Aguilar Carme Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut Calull Marta Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut Chromatographia Vieweg Verlag 73/1-2(2011-01-01), 83-91 0009-5893 73:1-2<83 2011 73 10337 https://doi.org/10.1007/s10337-010-1817-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10337-010-1817-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maijó Irene Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut NATIONALLICENCE 700 1- Borrull Francesc Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut NATIONALLICENCE 700 1- Aguilar Carme Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut NATIONALLICENCE 700 1- Calull Marta Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili, C/Marcel.lí Domingo s/n, 43007, Tarragona, Spain aut NATIONALLICENCE 773 0- Chromatographia Vieweg Verlag 73/1-2(2011-01-01), 83-91 0009-5893 73:1-2<83 2011 73 10337 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer