caa a22 4500 445802626 CHVBK 20180317145146.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10337-011-2014-6 doi (NATIONALLICENCE)springer-10.1007/s10337-011-2014-6 Enantioseparation Using Chitosan Tris(3-chlorophenylcarbamate) as a Chiral Stationary Phase for HPLC [Elektronische Daten] [Xiaoqian Han, Lili An, Hong Cui, Hongyu Li, Wanliang Liu] A novel chiral stationary phase (CSP) consisting of a silica-based chitosan tris(3-chlorophenylcarbamate) derivative was used for the enantioseparation of nine racemic compounds in the normal phase mode by high-performance liquid chromatography (LC). The influence of the type and percentage of modifier in the mobile phase on the optimization of the resolution was investigated. The resolution of epoxiconazole using this system was compared with those achieved using commercially available Chiralcel® OD-H and Chiralpak® AD-H columns. Among the tested racemates, seven racemic compounds were separated most quickly on the CSP of chitosan tris(3-chlorophenylcarbamate). Baseline or near-baseline separation was achieved for benzoin, penconazole, hexaconazole, and epoxiconazole, while the others were partially separated. The enantioseparation results for epoxiconazole were not inferior to those of commercially available Chiralcel® OD-H and Chiralpak® AD-H columns. Springer-Verlag, 2011 Column liquid chromatography nationallicence Enantioseparation nationallicence Chitosan tris(3-chlorophenylcarbamate) nationallicence Chiral stationary phase nationallicence Han Xiaoqian School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut An Lili School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut Cui Hong School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut Li Hongyu School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut Liu Wanliang School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut Chromatographia Springer-Verlag 73/11-12(2011-06-01), 1043-1047 0009-5893 73:11-12<1043 2011 73 10337 https://doi.org/10.1007/s10337-011-2014-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10337-011-2014-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Han Xiaoqian School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- An Lili School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Cui Hong School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Li Hongyu School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut NATIONALLICENCE 700 1- Liu Wanliang School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070, Lanzhou, People's Republic of China aut NATIONALLICENCE 773 0- Chromatographia Springer-Verlag 73/11-12(2011-06-01), 1043-1047 0009-5893 73:11-12<1043 2011 73 10337 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer