caa a22 4500 445803673 CHVBK 20180317145150.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10337-011-2090-7 doi (NATIONALLICENCE)springer-10.1007/s10337-011-2090-7 Determination of Chlorantraniliprole Residues in Corn and Soil by UPLC-ESI-MS/MS and Its Application to a Pharmacokinetic Study [Elektronische Daten] [Fengshou Dong, Jun Xu, Xingang Liu, Jing Li, Yuanbo Li, Zhiqiang Kong, Weili Shan, Zuntao Zheng, Yongquan Zheng] A rapid, highly sensitive, and selective method was developed for the determination of the insecticide chlorantraniliprole (CAP) in corn and soil using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Samples were extracted with acetonitrile, and aliquots were cleaned with solid-phase extraction cartridges. Two precursor-product ion transitions for CAP were measured and evaluated to provide maximum confidence in the results. Average recovery for soil, corn grain, and corn straw at different levels (5 or 10, 40, and 100μgkg−1) ranged from 74.9 to 97.5%, with intra-day relative standard deviation (RSD) values of 1.9-11.3% and inter-day RSD values of 4.7-10.4%. Coefficients of determination (R 2) of 0.9988 or higher were achieved for CAP in soil, corn grain, and corn straw matrix calibration curves, from 5 to 1,000μgL−1. The CAP limits of quantitation in soil, corn grain, and straw were determined to be 5, 10, and 10μgkg−1, respectively, which were much lower than the maximum residue levels established by the Environmental Protection Agency of United States. UPLC-MS/MS was used to determine the CAP residues in real corn and soil for studies on their dissipation. The trial results showed that the half-lives of CAP changed from 12.6 to 23.1days in soils and ranged from 4.9 to 5.4days in corn straws in the districts of Henan and Shandong, and the average levels of CAP residues in corn grains were all <0.01mgkg−1 with a harvest withholding period of 180days. Springer-Verlag, 2011 UPLC-MS/MS nationallicence Chlorantraniliprole nationallicence Dissipation nationallicence Corn nationallicence Soil nationallicence Dong Fengshou Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Xu Jun Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Liu Xingang Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Li Jing Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Li Yuanbo Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Kong Zhiqiang Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Shan Weili Institute for the Control of Agrochemicals, Ministry of Agriculture, 100125, Beijing, China aut Zheng Zuntao Institute for the Control of Agrochemicals, Ministry of Agriculture, 100125, Beijing, China aut Zheng Yongquan Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut Chromatographia Springer-Verlag 74/5-6(2011-09-01), 399-406 0009-5893 74:5-6<399 2011 74 10337 https://doi.org/10.1007/s10337-011-2090-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10337-011-2090-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dong Fengshou Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Xu Jun Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Liu Xingang Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Li Jing Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Li Yuanbo Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Kong Zhiqiang Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 700 1- Shan Weili Institute for the Control of Agrochemicals, Ministry of Agriculture, 100125, Beijing, China aut NATIONALLICENCE 700 1- Zheng Zuntao Institute for the Control of Agrochemicals, Ministry of Agriculture, 100125, Beijing, China aut NATIONALLICENCE 700 1- Zheng Yongquan Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, 100193, Beijing, China aut NATIONALLICENCE 773 0- Chromatographia Springer-Verlag 74/5-6(2011-09-01), 399-406 0009-5893 74:5-6<399 2011 74 10337 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer