caa a22 4500 445803819 CHVBK 20180317145150.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s10337-011-2023-5 doi (NATIONALLICENCE)springer-10.1007/s10337-011-2023-5 Ionic Liquid-Based Ultrasonic/Microwave-Assisted Extraction Combined with UPLC for the Determination of Anthraquinones in Rhubarb [Elektronische Daten] [Chunxia Lu, Hongxin Wang, Wenping Lv, Chaoyang Ma, Pao Xu, Jian Zhu, Jun Xie, Bo liu, Qunlan Zhou] Ionic liquid-based ultrasonic/microwave-assisted extraction (IL-UMAE) of five anthraquinones (physcion, chrysophanol, emodin, rhein, and aloe-emodin) from rhubarb was first studied. Several parameters of UMAE were optimized, and the results were compared with of the heat-reflux extraction (HRE), ultrasound, and microwave-assisted extraction (MAE and UAE). The optimal UMAE conditions were as follows: the solvent was 2.0molL−1 1-butyl-3-methylimidazolium bromide [bmim]Br solution, the ration of solid/liquid (gmL−1) was 1:15, time was 2min, and microwave power was 500W. Under these UMAE conditions, total content of five anthraquinones was 28.00mgg−1. Compared with the conventional HRE, regular MAE and UAE techniques, the proposed approach exhibited higher efficiency (18.90-24.40% enhanced) and shorter extraction time (from 6h to 2min). The anthraquinones were then determined by ultra performance liquid chromatography (UPLC). Based on optimized conditions, contents of physcion, chrysophanol, emodin, rhein and aloe-emodin in rhubarb collected from different cultivated areas were 0.68-2.99, 5.03-15.40, 0.48-4.34, 0.025-3.93 and 0.26-2.56mgg−1, respectively. This study suggests that IL-UMAE was an efficient, rapid, simple and green preparation technique. Springer-Verlag, 2011 Ultra performance liquid chromatography nationallicence Ultrasonic/microwave-assisted extraction nationallicence Ionic liquid nationallicence Anthraquinones nationallicence Rhubarb nationallicence Lu Chunxia State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut Wang Hongxin State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut Lv Wenping State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut Ma Chaoyang State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut Xu Pao Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut Zhu Jian Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut Xie Jun Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut liu Bo Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut Zhou Qunlan Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut Chromatographia Springer-Verlag 74/1-2(2011-07-01), 139-144 0009-5893 74:1-2<139 2011 74 10337 https://doi.org/10.1007/s10337-011-2023-5 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10337-011-2023-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lu Chunxia State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Wang Hongxin State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Lv Wenping State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Ma Chaoyang State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 214122, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Xu Pao Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Zhu Jian Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Xie Jun Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- liu Bo Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Qunlan Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Key Open Lab for Genetic Breeding of Aquatic Animals and Aquaculture Biology, Ministry of Agriculture, Shanshui East Road No. 9, 214081, Wuxi, People's Republic of China aut NATIONALLICENCE 773 0- Chromatographia Springer-Verlag 74/1-2(2011-07-01), 139-144 0009-5893 74:1-2<139 2011 74 10337 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer