caa a22 4500 445803991 CHVBK 20180317145151.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10337-011-2148-6 doi (NATIONALLICENCE)springer-10.1007/s10337-011-2148-6 Determination of Volatile Nitrosamines in Latex Products by HS-SPME-GC-MS [Elektronische Daten] [Di Feng, Luo Liu, Liyuan Zhao, Qingfeng Zhou, Tianwei Tan] Nitrosamines which have been detected in various latex products are carcinogens. The method for determination of volatile nitrosamines in latex products was developed using a combination of headspace solid phase micro-extraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS). A carboxen/polydimethylsiloxane (CAR/PDMS) fiber was used for HS-SPME involving the following variables: (1) agitation conditions, (2) extraction temperature (3) extraction time, and (4) salt concentration. The instrument performances of three detection systems including GC combined thermal energy analyzer, nitrogen chemiluminescence detector and MS were evaluated. The agitation conditions including magnetic stirring and ultrasonication were investigated by the comparison of extraction efficiency of HS-SPME for nitrosamines. Obtained optimal detection conditions of nitrosamines were HS-SPME at 45°C for 60min assisted with magnetic stirring and saturated NaCl followed by GC-MS. To evaluate this method performance, the commercial products including eleven latex products (gloves, balloons and condoms) and four liquid silicone nipples were analyzed with the method. The results revealed that the method is suitable for simple and effective determination of nitrosamines in latex products. The advantage of this HS-SPME-GC-MS method is simple treatment, fast analysis, adequate sensitivity and without organic solvent. Springer-Verlag, 2011 GC-MS nationallicence SPME nationallicence Nitrosamines nationallicence Latex products nationallicence Feng Di Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut Liu Luo Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut Zhao Liyuan Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut Zhou Qingfeng Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut Tan Tianwei Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut Chromatographia Springer-Verlag 74/11-12(2011-12-01), 817-825 0009-5893 74:11-12<817 2011 74 10337 https://doi.org/10.1007/s10337-011-2148-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10337-011-2148-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Feng Di Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut NATIONALLICENCE 700 1- Liu Luo Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut NATIONALLICENCE 700 1- Zhao Liyuan Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut NATIONALLICENCE 700 1- Zhou Qingfeng Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut NATIONALLICENCE 700 1- Tan Tianwei Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China aut NATIONALLICENCE 773 0- Chromatographia Springer-Verlag 74/11-12(2011-12-01), 817-825 0009-5893 74:11-12<817 2011 74 10337 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer