caa a22 4500 445805226 CHVBK 20180317145154.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00453-010-9429-6 doi (NATIONALLICENCE)springer-10.1007/s00453-010-9429-6 A New Algorithm for a Field Splitting Problem in Intensity-Modulated Radiation Therapy [Elektronische Daten] [Danny Chen, Konrad Engel, Chao Wang] Intensity-modulated radiation therapy (IMRT) is a modern cancer treatment technique with which optimized radiation fluence distributions, called intensity maps (IMs), are delivered to the target tumors via the help of a device called multileaf collimator (MLC), in order to produce homogeneous dose distributions of a prescribed amount at the target while sparing the surrounding organs and tissue. Due to the maximum leaf spread constraint of the MLCs, IMs whose widths exceed a given threshold cannot be delivered as a whole, and thus must be split into multiple subfields. The field splitting problems in IMRT normally aim to minimize the total beam-on time (i.e. the total time when a patient is exposed to actual irradiation during the delivery) of the resulting subfields. In this paper, we present a new efficient polynomial time algorithm for a general field splitting problem with guaranteed output optimality. Springer Science+Business Media, LLC, 2010 Matrix partition nationallicence Integer linear programming nationallicence Greedy method nationallicence Intensity-modulated radiation therapy nationallicence Field splitting nationallicence Chen Danny Department of Computer Science and Engineering, University of Notre Dame, 46556, Notre Dame, IN, USA aut Engel Konrad Institute for Mathematics, University of Rostock, 18051, Rostock, Germany aut Wang Chao Department of Computer Science and Engineering, University of Notre Dame, 46556, Notre Dame, IN, USA aut Algorithmica Springer-Verlag 61/3(2011-11-01), 656-673 0178-4617 61:3<656 2011 61 453 https://doi.org/10.1007/s00453-010-9429-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00453-010-9429-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Danny Department of Computer Science and Engineering, University of Notre Dame, 46556, Notre Dame, IN, USA aut NATIONALLICENCE 700 1- Engel Konrad Institute for Mathematics, University of Rostock, 18051, Rostock, Germany aut NATIONALLICENCE 700 1- Wang Chao Department of Computer Science and Engineering, University of Notre Dame, 46556, Notre Dame, IN, USA aut NATIONALLICENCE 773 0- Algorithmica Springer-Verlag 61/3(2011-11-01), 656-673 0178-4617 61:3<656 2011 61 453 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer