caa a22 4500 445807377 CHVBK 20180317145200.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00415-010-5898-4 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5898-4 Migration and multiple sclerosis in immigrants to Australia from United Kingdom and Ireland: a reassessment. I. Risk of MS by age at immigration [Elektronische Daten] [J. McLeod, S. Hammond, J. Kurtzke] A previous study of the prevalence of multiple sclerosis (MS) in 1981 among immigrants from the United Kingdom and Ireland to Australia found that the prevalence for those with age at immigration (AAI) under 15years of age did not differ from the older immigrants. We have reanalysed the original materials as well as census data for 1901-1981 for UKI and other high MS risk country immigrants. There was a highly significant trend in the prevalence rates of all Australians from New South Wales (NSW) to South Australia (SA) to Western Australia (WA) to Queensland (QLD). Rates by state among the Australian-born were almost identical to these, but there was no prevalence gradient for the UKI-born. The denominator population at risk of MS by AAI was calculated from special census tables of length of residence in Australia by age 0-79 in 1981 for UKI immigrants 1947-1981. The numerator was limited to the subset of 258 MS (Group II) also immigrating in 1947 and later, and age 0-79 in 1981. The absolute risk of MS for these migrants to the four states entering at age 0-14 was 22/100,000, significantly less than for all older age groups; age 15-39 immigrants had a risk of 54/100,000. Similar risk ratios for 0-14 versus 15-39 by state were 31 versus 61 (NSW), 29 versus 44 (QLD), 11 versus 50 (SA), 15 versus 51 (WA). The Author(s), 2011 Multiple sclerosis nationallicence Prevalence nationallicence Immigration nationallicence Risk nationallicence Australia nationallicence McLeod J. Department of Medicine, University of Sydney, NSW 2006, Camperdown, Australia aut Hammond S. Maynooth Neurology, NSW 2800, Orange, Australia aut Kurtzke J. Emeritus, Neurology, Georgetown University, Washington, DC, USA aut Journal of Neurology Springer-Verlag 258/6(2011-06-01), 1140-1149 0340-5354 258:6<1140 2011 258 415 https://doi.org/10.1007/s00415-010-5898-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5898-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McLeod J. Department of Medicine, University of Sydney, NSW 2006, Camperdown, Australia aut NATIONALLICENCE 700 1- Hammond S. Maynooth Neurology, NSW 2800, Orange, Australia aut NATIONALLICENCE 700 1- Kurtzke J. Emeritus, Neurology, Georgetown University, Washington, DC, USA aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/6(2011-06-01), 1140-1149 0340-5354 258:6<1140 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 445807377 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer