caa a22 4500 445807547 CHVBK 20180317145201.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00415-010-5895-7 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5895-7 MR neurography of sciatic nerve injection injury [Elektronische Daten] [Mirko Pham, Carsten Wessig, Jörg Brinkhoff, Karlheinz Reiners, Guido Stoll, Martin Bendszus] We report on magnetic resonance neurography (MRN) as a supplementary diagnostic tool in sciatic nerve injection injury. The object of the study was to test if T2-weighted (w) contrast within the sciatic nerve serves as an objective criterion for sciatic injection injury. Three patients presented with acute sensory and/or motor complaints in the distribution of the sciatic nerve after dorsogluteal injection and underwent MRN covering gluteal, thigh and knee levels. Native and contrast-enhanced T1-w images were employed to identify the tibial and peroneal division of the sciatic nerve while T2-w images with fat suppression allowed visualization of the site and extent of the nerve lesion. MRN in the two patients with clinically severe sensory and motor impairment correctly depicted sciatic injury: continuity of the T2-w lesion within the nerve at the lesion site and distal to it corresponded well to severe injury confirmed by NCS/EMG as axonotmetic or neurotmetic. Topography of the T2-w lesion on cross-section corresponded to predominant peroneal involvement; moreover, associated denervation patterns of distal target muscles were revealed. One of these patients completely recovered with concomitant complete regression of MRN abnormalities on follow-up. The third patient experienced transient sensory and mild motor impairment with complete recovery after 2weeks. In this patient, T2-w signal within the nerve and distal target muscles remained normal indicating only mild, non-axonal nerve affliction. Our case series shows that MRN can be very useful in precisely determining the site of sciatic injection injury and may provide diagnostic criteria for the assessment of lesion severity and recovery. Springer-Verlag, 2011 Peripheral nervous system nationallicence Magnetic resonance imaging nationallicence Magnetic resonance neurography nationallicence Injection injury nationallicence Sciatic neuropathy nationallicence Nerve regeneration nationallicence Pham Mirko Department of Neuroradiology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany aut Wessig Carsten Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut Brinkhoff Jörg Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut Reiners Karlheinz Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut Stoll Guido Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut Bendszus Martin Department of Neuroradiology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany aut Journal of Neurology Springer-Verlag 258/6(2011-06-01), 1120-1125 0340-5354 258:6<1120 2011 258 415 https://doi.org/10.1007/s00415-010-5895-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5895-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pham Mirko Department of Neuroradiology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany aut NATIONALLICENCE 700 1- Wessig Carsten Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut NATIONALLICENCE 700 1- Brinkhoff Jörg Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut NATIONALLICENCE 700 1- Reiners Karlheinz Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut NATIONALLICENCE 700 1- Stoll Guido Department of Neurology, University of Würzburg, Joseph-Schneider Str. 11, 97080, Würzburg, Germany aut NATIONALLICENCE 700 1- Bendszus Martin Department of Neuroradiology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/6(2011-06-01), 1120-1125 0340-5354 258:6<1120 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer