caa a22 4500 445808233 CHVBK 20180317145203.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s00415-011-5909-0 doi (NATIONALLICENCE)springer-10.1007/s00415-011-5909-0 Factors associated with time delay to carotid stenting in patients with a symptomatic carotid artery stenosis [Elektronische Daten] [Klaus Gröschel, Sonja Schnaudigel, Katrin Wasser, Sara Pilgram-Pastor, Ulrike Ernemann, Michael Knauth, Andreas Kastrup] Treatment of a symptomatic stenosis is known to be most beneficial within 14days after the presenting event but this can frequently not be achieved in daily practice. The aim of this study was the assessment of factors responsible for this time delay to treatment. A retrospective analysis of a prospective two-center CAS database was carried out to investigate the potential factors that influence a delayed CAS treatment. Of 374 patients with a symptomatic carotid stenosis, 59.1% were treated beyond ≥14days. A retinal TIA event (OR=3.59, 95% CI 1.47-8.74, p<0.01) was found to be a predictor for a delayed treatment, whereas the year of the intervention (OR=0.32, 95% CI 0.20-0.50, p<0.01) and a contralateral carotid occlusion (OR=0.42, 95% CI 0.21-0.86, p=0.02) were predictive of an early treatment. Similarly, within the subgroup of patients with transient symptoms, the year of the intervention (OR=0.28, 95% CI 0.14-0.59, p<0.01) was associated with an early treatment, whereas a retinal TIA as the qualifying event (OR=6.96, 95% CI 2.37-20.47, p<0.01) was associated with a delayed treatment. Treatment delay was most pronounced in patients with an amaurosis fugax, whereas a contralateral carotid occlusion led to an early intervention. Although CAS is increasingly performed faster in the last years, there is still scope for an even more accelerated treatment strategy, which might prevent future recurrent strokes prior to treatment. The Author(s), 2011 Symptomatic carotid stenosis nationallicence Stent nationallicence Stroke nationallicence Risk factors nationallicence Transient ischemic attack nationallicence ABCD2 score nationallicence Carotid artery stenting nationallicence Gröschel Klaus Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Schnaudigel Sonja Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Wasser Katrin Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Pilgram-Pastor Sara Department of Neuroradiology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Ernemann Ulrike Department of Neuroradiology, University of Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany aut Knauth Michael Department of Neuroradiology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Kastrup Andreas Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut Journal of Neurology Springer-Verlag 258/7(2011-07-01), 1228-1233 0340-5354 258:7<1228 2011 258 415 https://doi.org/10.1007/s00415-011-5909-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-011-5909-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gröschel Klaus Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Schnaudigel Sonja Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Wasser Katrin Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Pilgram-Pastor Sara Department of Neuroradiology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Ernemann Ulrike Department of Neuroradiology, University of Tübingen, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany aut NATIONALLICENCE 700 1- Knauth Michael Department of Neuroradiology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Kastrup Andreas Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/7(2011-07-01), 1228-1233 0340-5354 258:7<1228 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer