caa a22 4500 445808772 CHVBK 20180317145205.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00415-010-5782-2 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5782-2 Magnetic resonance imaging, risk factors and co-morbidities in children with cerebral palsy [Elektronische Daten] [Rajniti Prasad, Nishant Verma, A. Srivastava, B. Das, O. Mishra] Cerebral palsy (CP) continues to be a major problem in India. The present study provides an insight into the various clinical and neuroradiological correlates of CP. The study included 102 children with CP and was subjected to magnetic resonance imaging (MRI) of the brain. Forty-seven (46%) patients belonged to the 1-3years age group and 84 (82%) were born at term. Of 102 children, 39 (38%) were delivered at home. Based on their tone and topographic pattern of weakness, it was found that 47 (46%) had spastic diplegia and 35 (34%) spastic quadriplegia. Hemiplegic, dystonic, and atonic CP accounted for the remaining 20%. The occurrence of severe birth asphyxia, which is rarely seen in developed countries, continues to be a major problem in developing countries, and accounted 64 (62%) of the patients. Cognitive delay (82%) was the most common co-morbidity, followed by seizure disorder (52%), feeding difficulties (22%) and visual abnormalities (29%). Ninety-one (89%) children had an abnormal MRI. Periventricular white matter injury (PWMI) was observed in 48 (47.1%), followed by diffuse encephalopathy (29%). Focal lesions (6%) and malformations (3%) were less common. In children with spastic diplegia, PWMI was the most common MRI abnormality, whereas in spastic quadriplegia, diffuse encephalopathy was most common. MRI scans help in revealing the pathologic basis of CP and had strong correlations with clinical findings. Springer-Verlag, 2010 Cerebral palsy (CP) nationallicence Magnetic resonance imaging (MRI) nationallicence Spastic diplegia nationallicence Spastic quadriplegia nationallicence Periventricular white matter injury (PWMI) nationallicence Prasad Rajniti Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut Verma Nishant Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut Srivastava A. Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India aut Das B. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut Mishra O. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut Journal of Neurology Springer-Verlag 258/3(2011-03-01), 471-478 0340-5354 258:3<471 2011 258 415 https://doi.org/10.1007/s00415-010-5782-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5782-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Prasad Rajniti Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut NATIONALLICENCE 700 1- Verma Nishant Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut NATIONALLICENCE 700 1- Srivastava A. Department of Radiodiagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India aut NATIONALLICENCE 700 1- Das B. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut NATIONALLICENCE 700 1- Mishra O. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/3(2011-03-01), 471-478 0340-5354 258:3<471 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer