caa a22 4500 445808896 CHVBK 20180317145205.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00415-010-5778-y doi (NATIONALLICENCE)springer-10.1007/s00415-010-5778-y Spontaneous arm movement activity assessed by accelerometry is a marker for early recovery after stroke [Elektronische Daten] [Rüdiger Seitz, Tim Hildebold, Karin Simeria] The factors determining recovery from hemiparetic stroke are manifold. We studied spontaneous arm movement activity in the acute phase after stroke as a predictor of recovery. Included in this prospective study were 25 patients (63±10years; 9 women, 16 men) with acute middle cerebral artery stroke and 7 control patients without neurological disease (61±14years; 3 women, 4 men). Movement activity was measured continuously for 4days in both arms using Actiwatches and analysed off-line. Movement activity of the nonaffected arm ranged from <10 to >16h per day in the stroke patients. Nine stroke patients with an initial decline in arm movement activity showed no increase in movement activity in either arm over 4days after stroke, and the other 16 patients improved steadily after admission (p<0.003). C-reactive protein was elevated in the non-recovering patients (4.4±4.9mg/dl) related to a low number of waking hours (r=−0.512, p<0.01). Stroke severity, location and treatment, as well as arterial blood pressure (162±21mmHg) and body temperature (36.9±06°C) were not different among the groups. The impairment was still different among the two groups 3months after stroke. Our results support the notion that in the acute stage after middle cerebral artery stroke there are patients with a secondary decline in general motor activity related to an enhanced sleep demand as assessed with accelerometry. This impairment was related to elevated C-reactive protein. Springer-Verlag, 2010 Actiwatch nationallicence Accelerometry nationallicence Stroke nationallicence Recovery nationallicence Sleep nationallicence Seitz Rüdiger Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut Hildebold Tim Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut Simeria Karin Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut Journal of Neurology Springer-Verlag 258/3(2011-03-01), 457-463 0340-5354 258:3<457 2011 258 415 https://doi.org/10.1007/s00415-010-5778-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5778-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Seitz Rüdiger Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Hildebold Tim Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 700 1- Simeria Karin Department of Neurology, University Hospital Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/3(2011-03-01), 457-463 0340-5354 258:3<457 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer