caa a22 4500 445809248 CHVBK 20180317145206.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00415-011-6015-z doi (NATIONALLICENCE)springer-10.1007/s00415-011-6015-z Surviving stiff-person syndrome: a case report [Elektronische Daten] [Sharmilee Gnanapavan, Angela Vincent, Gavin Giovannoni] Stiff-person syndrome (SPS) is a rare condition of progressive muscular rigidity and spasm, frequently accompanied by other autoimmune conditions, an association which has been further strengthened by the discovery of anti-GAD antibodies and the response of SPS to immunotherapies. Intravenous immunoglobulin (IVIg) is the mainstay therapy. Because of the rarity of the GAD antibody associated conditions, most of the information regarding treatment is case series and individual case reports. Here we describe the 15year long management of a subject with SPS who has had a favourable outcome. Springer-Verlag, 2011 Stiff-person syndrome nationallicence GAD antibody nationallicence IVIg nationallicence Rituximad nationallicence Sirolimus nationallicence Gnanapavan Sharmilee Department of Neuroimmunology, Institute of Neurology, Queen Square, WC1N 3BG, London, UK aut Vincent Angela Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, Oxford, UK aut Giovannoni Gavin Neuroscience Centre, Barts and The London School of Medicine and Dentistry, London, UK aut Journal of Neurology Springer-Verlag 258/10(2011-10-01), 1898-1900 0340-5354 258:10<1898 2011 258 415 https://doi.org/10.1007/s00415-011-6015-z text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-011-6015-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gnanapavan Sharmilee Department of Neuroimmunology, Institute of Neurology, Queen Square, WC1N 3BG, London, UK aut NATIONALLICENCE 700 1- Vincent Angela Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, Oxford, UK aut NATIONALLICENCE 700 1- Giovannoni Gavin Neuroscience Centre, Barts and The London School of Medicine and Dentistry, London, UK aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/10(2011-10-01), 1898-1900 0340-5354 258:10<1898 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer