caa a22 4500 445809671 CHVBK 20180317145207.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00415-010-5791-1 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5791-1 Fasciculations and cramps: how benign? Report of four cases progressing to ALS [Elektronische Daten] [Varun Singh, John Gibson, Brendan McLean, Mike Boggild, Nicholas Silver, Richard White] Clinical diagnosis of amyotrophic lateral sclerosis (ALS) in patients presenting with cramps and fasciculations may not be evident at the first consultation. Sequential reviews, clinical and neurophysiological, form an important part of clinical practice in such cases. Recent attempts to delineate a more benign group with cramps and fasciculations have lacked information on the long term profile, both clinical and neurophysiological. Four patients who were initially diagnosed as suffering from benign cramps and fasciculations, but who subsequently progressed to ALS, are described. We propose that a diagnosis of benign cramps and fasciculations should not be considered secure without a minimum follow up of 4-5years. Springer-Verlag, 2010 ALS nationallicence Fasciculation nationallicence Cramps nationallicence Myokymia nationallicence Cramp-fasciculation syndrome nationallicence Singh Varun Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut Gibson John Nuffield Hospital, PL6 8BG, Plymouth, Devon, UK aut McLean Brendan Department of Neurology, The Royal Cornwall Hospitals NHS Trust, Treliske, TR1 3LJ, Truro, Cornwall, UK aut Boggild Mike Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut Silver Nicholas Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut White Richard Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut Journal of Neurology Springer-Verlag 258/4(2011-04-01), 573-578 0340-5354 258:4<573 2011 258 415 https://doi.org/10.1007/s00415-010-5791-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5791-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Singh Varun Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut NATIONALLICENCE 700 1- Gibson John Nuffield Hospital, PL6 8BG, Plymouth, Devon, UK aut NATIONALLICENCE 700 1- McLean Brendan Department of Neurology, The Royal Cornwall Hospitals NHS Trust, Treliske, TR1 3LJ, Truro, Cornwall, UK aut NATIONALLICENCE 700 1- Boggild Mike Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut NATIONALLICENCE 700 1- Silver Nicholas Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut NATIONALLICENCE 700 1- White Richard Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7AJ, Liverpool, UK aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/4(2011-04-01), 573-578 0340-5354 258:4<573 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer