caa a22 4500 445809701 CHVBK 20180317145207.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00415-010-5865-0 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5865-0 Magnetic resonance imaging in progressive supranuclear palsy [Elektronische Daten] [M. Stamelou, S. Knake, W. Oertel, G. Höglinger] Progressive supranuclear palsy (PSP) is a tauopathy, presenting clinically most often with a symmetrical akinetic-rigid syndrome, postural instability, supranuclear gaze palsy and frontal dementia. In the absence of reliably validated biomarkers, the diagnosis of PSP in vivo is presently based on clinical criteria, which to date do not include supporting imaging findings, as is accepted for other neurodegenerative diseases. However, data from conventional magnetic resonance imaging (MRI) and various advanced MRI techniques including magnetic resonance volumetry, voxel-based morphometry, diffusion-weighted and diffusion-tensor imaging, magnetization transfer imaging and proton resonance spectroscopy suggest that MRI can contribute valuable information for the differential diagnosis of PSP. We review here the presently published literature concerning MRI in PSP and discuss the potential role of MRI in differentiating PSP from other parkinsonian syndromes. Springer-Verlag, 2010 Progressive supranuclear palsy nationallicence Magnetic resonance imaging nationallicence Voxel-based morphometry nationallicence Diffusion-tensor imaging nationallicence Proton magnetic resonance spectroscopy nationallicence Stamelou M. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut Knake S. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut Oertel W. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut Höglinger G. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut Journal of Neurology Springer-Verlag 258/4(2011-04-01), 549-558 0340-5354 258:4<549 2011 258 415 https://doi.org/10.1007/s00415-010-5865-0 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5865-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stamelou M. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut NATIONALLICENCE 700 1- Knake S. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut NATIONALLICENCE 700 1- Oertel W. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut NATIONALLICENCE 700 1- Höglinger G. Department of Neurology, Philipps University, Rudolf-Bultmann Str. 8, 35033, Marburg, Germany aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/4(2011-04-01), 549-558 0340-5354 258:4<549 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer