caa a22 4500 445809817 CHVBK 20180317145208.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00415-011-5972-6 doi (NATIONALLICENCE)springer-10.1007/s00415-011-5972-6 How well do we recognise non-motor symptoms in a British Parkinson's disease population? [Elektronische Daten] [Michele Hu, Jonathan Cooper, Rebecca Beamish, Emma Jones, Richard Butterworth, Lesley Catterall, Yoav Ben-Shlomo] Although awareness of non-motor symptoms in Parkinson's disease (PD) has recently increased, little is known about their recognition and treatment in routine clinical practice. We therefore applied non-motor rating scales for dementia, depression, anxiety and excessive daytime sleepiness to a community-ascertained cohort of 202 PD patients. Hospital case notes were reviewed for evidence that the non-motor problems had been recognized and whether any action had been taken to ameliorate or assess these symptoms. The prevalence of each non-motor problem was as follows: dementia 25.3% (95% CI 19.0, 32.4), depression 37.3% (95% CI 30.6, 44.4), anxiety 31.3% (95% CI 25.0, 38.2), excessive daytime sleepiness 59.4% (95% CI 52.2, 66.3). However, these features were only recognised in 27.2, 38.7, 9.5, and 12.8%, respectively. We did not identify any specific factor that predicted under-recognition. Our study shows that when rating scales are applied to formally assess for non-motor symptoms a large clinical ‘iceberg effect' emerges with the majority of symptoms going unrecognised and untreated. Springer-Verlag, 2011 Parkinson's disease nationallicence Non-motor symptoms nationallicence Recognition nationallicence Hu Michele Department of Neurology, Milton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals, Oxford, UK aut Cooper Jonathan Department of General Medicine, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK aut Beamish Rebecca Department of General Medicine, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK aut Jones Emma Milton Keynes Neuro-Rehabilitation Unit, Milton Keynes, UK aut Butterworth Richard Department of Neurology, Milton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals, Oxford, UK aut Catterall Lesley Thames Valley Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), Oxford, UK aut Ben-Shlomo Yoav Department of Social Medicine, University of Bristol, Bristol, UK aut Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1513-1517 0340-5354 258:8<1513 2011 258 415 https://doi.org/10.1007/s00415-011-5972-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-011-5972-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hu Michele Department of Neurology, Milton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals, Oxford, UK aut NATIONALLICENCE 700 1- Cooper Jonathan Department of General Medicine, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK aut NATIONALLICENCE 700 1- Beamish Rebecca Department of General Medicine, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK aut NATIONALLICENCE 700 1- Jones Emma Milton Keynes Neuro-Rehabilitation Unit, Milton Keynes, UK aut NATIONALLICENCE 700 1- Butterworth Richard Department of Neurology, Milton Keynes Hospital NHS Foundation Trust and Oxford Radcliffe Hospitals, Oxford, UK aut NATIONALLICENCE 700 1- Catterall Lesley Thames Valley Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), Oxford, UK aut NATIONALLICENCE 700 1- Ben-Shlomo Yoav Department of Social Medicine, University of Bristol, Bristol, UK aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1513-1517 0340-5354 258:8<1513 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer