caa a22 4500 445809868 CHVBK 20180317145208.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00415-011-5948-6 doi (NATIONALLICENCE)springer-10.1007/s00415-011-5948-6 A cross-sectional study of quality of life in incident stroke survivors in rural northern Tanzania [Elektronische Daten] [Suzanne Howitt, Matthew Jones, Ahmed Jusabani, William Gray, Eric Aris, Ferdinand Mugusi, Mark Swai, Richard Walker] The aim of this study was to evaluate changes to, and predictors of, quality of life (QOL) in a community-based cohort of stroke survivors from an earlier stroke incidence study in rural northern Tanzania. Patients were assessed 1-5years after their incident stroke. The study cohort was compared with an age- and sex-matched control group from the same rural district within a cross-sectional design. Patients and controls were asked a series of questions relating to their QOL [World Health Organization quality of life, abbreviated version (WHOQOL-BREF)], levels of anxiety and depression [hospital anxiety and depression (HAD) scale], cognitive function [community screening instrument for dementia (CSI-D) screening tool], socioeconomic status and demographic characteristics (e.g. age, sex, education and abode). Patients were further assessed for functional outcome and disability (Barthel index, modified Rankin scale), post-stroke care and psychosocial functioning. Patients (n=58) were found to have significantly lower QOL than controls (n=58) in all six domains of the WHOQOL-BREF. Gender, socioeconomic status, cognitive function and time elapsed since stroke were not associated with QOL. Older patients and those with more impaired motor function and disability (Barthel index, modified Rankin score) had significantly poorer physical health-related QOL. Greater anxiety and depression, reduced muscle power and less involvement in social events were significantly correlated with lower physical and psychological health-related QOL. To our knowledge, this is the first long-term study of QOL in survivors of incident stroke in Sub-Saharan Africa (SSA). Poorer QOL was associated with greater levels of physical disability, anxiety and depression and reduced social interaction. Demographic factors appear to be much less significant. Modifying these QOL predictors could be important in planning effective post-stroke care within a stretched healthcare system. Springer-Verlag, 2011 Stroke nationallicence Tanzania nationallicence Quality of life nationallicence Community-dwelling nationallicence Howitt Suzanne South Tyneside NHS Foundation Trust, South Tyneside District Hospital, Harton Lane, South Shields, NE34 0PL, Tyne and Wear, UK aut Jones Matthew Gateshead Health NHS Foundation Trust, Queen Elizabeth Hospital, Sheriff Hill, NE9 6SX, Gateshead, UK aut Jusabani Ahmed Department of Radiology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania aut Gray William Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, NE29 8NH, Tyne and Wear, UK aut Aris Eric Department of Medicine, Muhimbili University College Hospital, Dar-es-Salaam, Tanzania aut Mugusi Ferdinand Department of Medicine, Muhimbili University College Hospital, Dar-es-Salaam, Tanzania aut Swai Mark Kilimanjaro Christian Medical Centre, Moshi, Kilimanjaro Region, Tanzania aut Walker Richard Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, NE29 8NH, Tyne and Wear, UK aut Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1422-1430 0340-5354 258:8<1422 2011 258 415 https://doi.org/10.1007/s00415-011-5948-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-011-5948-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Howitt Suzanne South Tyneside NHS Foundation Trust, South Tyneside District Hospital, Harton Lane, South Shields, NE34 0PL, Tyne and Wear, UK aut NATIONALLICENCE 700 1- Jones Matthew Gateshead Health NHS Foundation Trust, Queen Elizabeth Hospital, Sheriff Hill, NE9 6SX, Gateshead, UK aut NATIONALLICENCE 700 1- Jusabani Ahmed Department of Radiology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania aut NATIONALLICENCE 700 1- Gray William Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, NE29 8NH, Tyne and Wear, UK aut NATIONALLICENCE 700 1- Aris Eric Department of Medicine, Muhimbili University College Hospital, Dar-es-Salaam, Tanzania aut NATIONALLICENCE 700 1- Mugusi Ferdinand Department of Medicine, Muhimbili University College Hospital, Dar-es-Salaam, Tanzania aut NATIONALLICENCE 700 1- Swai Mark Kilimanjaro Christian Medical Centre, Moshi, Kilimanjaro Region, Tanzania aut NATIONALLICENCE 700 1- Walker Richard Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, NE29 8NH, Tyne and Wear, UK aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1422-1430 0340-5354 258:8<1422 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer