caa a22 4500 445809981 CHVBK 20180317145208.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00415-011-5969-1 doi (NATIONALLICENCE)springer-10.1007/s00415-011-5969-1 The health-related, social, and economic consequences of parkinsonism: a controlled national study [Elektronische Daten] [Poul Jennum, Marielle Zoetmulder, Lise Korbo, Jakob Kjellberg] Parkinson's disease (PD) and atypical parkinsonism (AP) cause a significant socioeconomic burden, but there is insufficient information about the total disease burden at a national level. Thus, the goal of this study was to estimate the excess direct and indirect costs of PD and AP in a national sample. Using records from the Danish National Patient Registry (1997-2007), 13,400 PD and 647 AP patients were identified and compared with, respectively, 53,600 and 2,588 control cases randomly selected with respect to age, gender, civil status, and geographic location. Direct costs including frequencies of primary and sector contacts and procedures, and medication from primary and secondary sectors were obtained from the Danish Ministry of Health, the Danish Medicines Agency, and the National Health Security. Indirect costs, which included labor supply and social transfer payments, were based on income data derived from the Coherent Social Statistics. Patients with PD and AP had significantly higher rates of health-related contact and medication use and a higher socioeconomic cost. Furthermore, they had very low employment rates, and those in employment had a lower income level than employed control subjects. The annual mean excess health-related cost was €6,500 ($8,975/£5,543) and €9,771 ($13,491/£8,332) for each patient with PD and AP, respectively. In addition, the patients with PD and AP received an annual mean excess social transfer income of €324 (£276/$447) and €844 (£719/$1,165), respectively. The employment- and health-related consequences could be identified up to 8years before the first diagnosis and increased with disease advancement. PD and AP have major socioeconomic consequences for patients and society. The health effects are present for up to more than 8years before a diagnosis of PD/AP. Springer-Verlag, 2011 Parkinson's disease nationallicence Illness costs nationallicence Health costs nationallicence Economic burden nationallicence Employment nationallicence Jennum Poul Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, 2600, Glostrup, Denmark aut Zoetmulder Marielle Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, 2600, Glostrup, Denmark aut Korbo Lise Department of Neurology, Bispebjerg Hospital, 2400, NV Copenhagen, Denmark aut Kjellberg Jakob Danish Institute for Health Services Research, Copenhagen, Denmark aut Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1497-1506 0340-5354 258:8<1497 2011 258 415 https://doi.org/10.1007/s00415-011-5969-1 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-011-5969-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jennum Poul Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, 2600, Glostrup, Denmark aut NATIONALLICENCE 700 1- Zoetmulder Marielle Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Center for Healthy Aging, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, 2600, Glostrup, Denmark aut NATIONALLICENCE 700 1- Korbo Lise Department of Neurology, Bispebjerg Hospital, 2400, NV Copenhagen, Denmark aut NATIONALLICENCE 700 1- Kjellberg Jakob Danish Institute for Health Services Research, Copenhagen, Denmark aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/8(2011-08-01), 1497-1506 0340-5354 258:8<1497 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer