caa a22 4500 445810157 CHVBK 20180317145209.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00415-010-5821-z doi (NATIONALLICENCE)springer-10.1007/s00415-010-5821-z Assessment of gait parameters and fatigue in MS patients during inpatient rehabilitation: a pilot trial [Elektronische Daten] [Rosaria Sacco, Rita Bussman, Peter Oesch, Jürg Kesselring, Serafin Beer] Gait impairment and fatigue are common and disabling problems in multiple sclerosis (MS). Characterisation of abnormal gait in MS patients has been done mainly using observational studies and simple walking tests providing only limited quantitative and no qualitative data, or using intricate and time-consuming assessment procedures. In addition, the correlation of gait impairments with fatigue is largely unknown. The aim of this study was to characterise spatio-temporal gait parameters by a simple and easy-to-use gait analysis system (GAITRite®) in MS patients compared with healthy controls, and to analyse changes and correlation with fatigue during inpatient rehabilitation. Twenty-four MS patients (EDSS <6.5) admitted for inpatient rehabilitation and 19 healthy subjects were evaluated using the GAITRite® Functional Ambulation System. Between-group differences and changes of gait parameters during inpatient rehabilitation were analysed, and correlation with fatigue, using the Wurzburg Fatigue Inventory for Multiple Sclerosis (WEIMuS), was determined. Compared to healthy controls MS patients showed significant impairments in different spatio-temporal gait parameters, which showed a significant improvement during inpatient rehabilitation. Different gait parameters were correlated with fatigue physical score, and change of gait parameters was correlated with improvement of fatigue. Spatio-temporal gait analysis is helpful to assess specific walking impairments in MS patients and subtle changes during rehabilitation. Correlation with fatigue may indicate a possible negative impact of fatigue on rehabilitation outcome. Springer-Verlag, 2010 Multiple sclerosis nationallicence Gait nationallicence Fatigue nationallicence Rehabilitation nationallicence Sacco Rosaria Neurological Sciences Department, Second University of Napoli, Naples, Italy aut Bussman Rita Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut Oesch Peter Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut Kesselring Jürg Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut Beer Serafin Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut Journal of Neurology Springer-Verlag 258/5(2011-05-01), 889-894 0340-5354 258:5<889 2011 258 415 https://doi.org/10.1007/s00415-010-5821-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5821-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sacco Rosaria Neurological Sciences Department, Second University of Napoli, Naples, Italy aut NATIONALLICENCE 700 1- Bussman Rita Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut NATIONALLICENCE 700 1- Oesch Peter Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut NATIONALLICENCE 700 1- Kesselring Jürg Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut NATIONALLICENCE 700 1- Beer Serafin Department of Neurology and Neurorehabilitation and Research Department, Rehabilitation Center, 7317, Valens, Switzerland aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/5(2011-05-01), 889-894 0340-5354 258:5<889 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer