caa a22 4500 445810645 CHVBK 20180317145210.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00415-010-5730-1 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5730-1 Autonomic dysfunction in non-paraneoplastic sensory neuronopathy: beyond sensory abnormalities [Elektronische Daten] [Alfredo Damasceno, Marcondes França Jr., Halim Cury, Anamarli Nucci] Sensory neuronopathies (SN) represent a subgroup of peripheral nervous system disorders which are becoming increasingly recognized. Despite a few reports of autonomic dysfunction, this complication has not been fully appreciated. Autonomic function was quantified through tests of sympathetic and parasympathetic function (forming the Autonomic Tests Score, ATS), and through a 40-item questionnaire assessing autonomic symptoms (constituting the Autonomic Questionnaire Score, AQS). Twenty patients were enrolled. Forty-six age- and gender-matched controls were evaluated for the AQS and 15 for the ATS. All patients reported symptoms of autonomic dysfunction. Of the patients, 60% had one or more abnormal cardiovagal test, 60% orthostatic hypotension and 20% abnormal pupillary function. Their ATS was significantly different from the controls (p<0.0001). Neither the ATS nor AQS were different between groups of SN associated disorders. Autonomic dysfunction is a frequent and important complication in SN, and it does not seem to be related to a specific etiology, as previously thought. Springer-Verlag, 2010 Autonomic dysfunction nationallicence Clinical neurophysiology nationallicence Heart rate variability nationallicence Sensory ganglionopathy nationallicence Sensory neuronopathy nationallicence Damasceno Alfredo Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut França Jr. Marcondes Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut Cury Halim Departamento de Cardiologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut Nucci Anamarli Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut Journal of Neurology Springer-Verlag 258/2(2011-02-01), 231-237 0340-5354 258:2<231 2011 258 415 https://doi.org/10.1007/s00415-010-5730-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5730-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Damasceno Alfredo Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut NATIONALLICENCE 700 1- França Jr Marcondes Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut NATIONALLICENCE 700 1- Cury Halim Departamento de Cardiologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut NATIONALLICENCE 700 1- Nucci Anamarli Departamento de Neurologia, FCM-UNICAMP, CEP 13083-970, Campinas, SP, Brazil aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/2(2011-02-01), 231-237 0340-5354 258:2<231 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer