caa a22 4500 445810742 CHVBK 20180317145211.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00415-010-5729-7 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5729-7 FDG-PET SUV can distinguish between spinal sarcoidosis and myelopathy with canal stenosis [Elektronische Daten] [Ken Sakushima, Ichiro Yabe, Tohru Shiga, Moemi Yashima-Yamada, Sachiko Tsuji-Akimoto, Satoshi Terae, Hidenao Sasaki] Spinal cord sarcoidosis is a rare manifestation of sarcoidosis. Magnetic resonance imaging (MRI) of spinal cord sarcoidosis sometimes resembles that of the non-inflammatory spinal cord lesion. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is an effective method to detect both systemic and central nervous system lesions in sarcoidosis. This study compared the standard uptake value (SUV) of FDG-PET between spinal cord sarcoidosis and non-inflammatory spinal cord lesions. We retrospectively reviewed the records of patients who underwent both spinal MRI and FDG-PET scans. We used SUV to evaluate the FDG-PET uptake of the lesion. The region of interest was the center of high-intensity areas on T2-weighted MR images. We included three patients with spinal cord sarcoidosis, five with myelomalacia caused by cervical spondylosis or ossification of the posterior longitudinal ligament, one with spinal cord edema associated with cervical spondylosis, and one with spinal cord edema associated with dural arteriovenous fistula. The spinal cord sarcoidosis group had a significantly higher SUV (mean 4.38, range 3.30-4.93) than patients with the other diseases (mean 1.87, range 1.42-2.74). The SUV of FDG-PET thus may be able to distinguish spinal cord sarcoidosis from other non-inflammatory lesions. FDG-PET can play an important role in the diagnosis of spinal cord sarcoidosis because the gadolinium enhancement in MRI is sometimes seen in spondylotic myelopathy or vascular malformation. FDG-PET is informative for the accurate diagnosis of spinal cord sarcoidosis and may enable clinicians to start treatment at an earlier stage. Springer-Verlag, 2010 FDG-PET nationallicence Standard uptake value nationallicence Spinal cord sarcoidosis nationallicence Myelopathy nationallicence Canal stenosis nationallicence Sakushima Ken Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut Yabe Ichiro Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut Shiga Tohru Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut Yashima-Yamada Moemi Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut Tsuji-Akimoto Sachiko Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut Terae Satoshi Department of Radiology, Hokkaido University Hospital, Sapporo, Japan aut Sasaki Hidenao Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut Journal of Neurology Springer-Verlag 258/2(2011-02-01), 227-230 0340-5354 258:2<227 2011 258 415 https://doi.org/10.1007/s00415-010-5729-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5729-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sakushima Ken Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Yabe Ichiro Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Shiga Tohru Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Yashima-Yamada Moemi Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Tsuji-Akimoto Sachiko Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 700 1- Terae Satoshi Department of Radiology, Hokkaido University Hospital, Sapporo, Japan aut NATIONALLICENCE 700 1- Sasaki Hidenao Department of Neurology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, 060-8638, Sapporo, Japan aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/2(2011-02-01), 227-230 0340-5354 258:2<227 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer