caa a22 4500 445810882 CHVBK 20180317145211.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00415-010-5705-2 doi (NATIONALLICENCE)springer-10.1007/s00415-010-5705-2 Nocturia is an independent predictor of severe obstructive sleep apnea in patients with ischemic stroke [Elektronische Daten] [Chung-Yao Chen, Chih-Chin Hsu, Yu-Cheng Pei, Chung-Chieh Yu, Ying-Syuan Chen, Chia-Ling Chen] Severe obstructive sleep apnea (OSA) increases the risk of stroke recurrence and mortality after stroke. Since nocturia is common in post-stroke patients with OSA, this study explored the predictive role of nocturia for severe OSA in patients with ischemic stroke. This was a cross-sectional, prospective study involving 65 consecutive patients with ischemic stroke admitted to rehabilitation ward. All participants received polysomnography and clinical assessments, including a 3-day urinary frequency-volume recording. Differences in study variables between patients with and without severe OSA were compared, and logistic regression analyses with backward selection procedures were used to assess the relationship between OSA severity and nocturia. Patients with severe OSA were older (69.6±9.9 vs. 62.6±11.5year), had a significantly higher desaturation index (37.9±16.1 vs. 8.8±6.1episodes/night) and had a higher frequency of nocturia (2.2±1.0 vs. 1.5±0.8episodes/night) than those without. In addition, men with severe OSA had a larger neck circumference (409±26 vs. 381±32mm) than those without. The frequency of nocturia, age, sex, and interaction between sex and neck circumference remained significant in the final regression model for severe OSA. In this model, the area under the receiver operating characteristic curve was 0.87 (95% CI 0.79-0.96; P<0.001) with sensitivity and specificity of 80.6 and 82.8%, respectively. The odds ratio of nocturia was highest (3.5) among the four variables. Nocturia is an independent predictor for severe OSA, and the final prediction model might be used when screening for severe OSA in patients with ischemic stroke. Springer-Verlag, 2010 Nocturia nationallicence Sleep apnea nationallicence Obstructive nationallicence Brain infarction nationallicence Prediction nationallicence Chen Chung-Yao Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut Hsu Chih-Chin Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut Pei Yu-Cheng Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 5 Fu-Hsing, St. Kwei-Shan, 333, Tao-Yuan, Taiwan aut Yu Chung-Chieh Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan aut Chen Ying-Syuan Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut Chen Chia-Ling Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 5 Fu-Hsing, St. Kwei-Shan, 333, Tao-Yuan, Taiwan aut Journal of Neurology Springer-Verlag 258/2(2011-02-01), 189-194 0340-5354 258:2<189 2011 258 415 https://doi.org/10.1007/s00415-010-5705-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00415-010-5705-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Chung-Yao Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut NATIONALLICENCE 700 1- Hsu Chih-Chin Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut NATIONALLICENCE 700 1- Pei Yu-Cheng Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 5 Fu-Hsing, St. Kwei-Shan, 333, Tao-Yuan, Taiwan aut NATIONALLICENCE 700 1- Yu Chung-Chieh Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan aut NATIONALLICENCE 700 1- Chen Ying-Syuan Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan aut NATIONALLICENCE 700 1- Chen Chia-Ling Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 5 Fu-Hsing, St. Kwei-Shan, 333, Tao-Yuan, Taiwan aut NATIONALLICENCE 773 0- Journal of Neurology Springer-Verlag 258/2(2011-02-01), 189-194 0340-5354 258:2<189 2011 258 415 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer