caa a22 4500 445812540 CHVBK 20180317145216.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00419-011-0508-1 doi (NATIONALLICENCE)springer-10.1007/s00419-011-0508-1 Bio-optimum prestress in actin filaments with a polygonal cytoskeleton model [Elektronische Daten] [X. Zhou, H. Shen, H. Wu] Prestress in actin filaments plays an important role in the stability of cells and it strongly influences the cell stiffness. In this paper, we present a simple polygonal cytoskeleton model to study the influence of cell prestress. The existence of prestress is shown to facilitate cytoskeletal integrity. Remarkably, the optimum prestress is computed to be several kPa of extension, which is comparable to experimental results. This bio-self-optimized prestress can make the cells sufficiently stable, allowing them to endure external compressive loadings. The relationship between cell rigidity and the prestress is determined using the presented model and found to be linear, which also agrees with experimental results. Springer-Verlag, 2011 Actin filament nationallicence Prestress nationallicence Buckling nationallicence Optimization nationallicence Zhou X. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut Shen H. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut Wu H. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut Archive of Applied Mechanics Springer-Verlag 81/11(2011-11-01), 1651-1658 0939-1533 81:11<1651 2011 81 419 https://doi.org/10.1007/s00419-011-0508-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00419-011-0508-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zhou X. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut NATIONALLICENCE 700 1- Shen H. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut NATIONALLICENCE 700 1- Wu H. Department of Modern Mechanics, CAS Key Laboratory of Materials Behavior and Design, University of Science and Technology of China, 230027, Hefei, Anhui, People's Republic of China aut NATIONALLICENCE 773 0- Archive of Applied Mechanics Springer-Verlag 81/11(2011-11-01), 1651-1658 0939-1533 81:11<1651 2011 81 419 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer